肺段切除和肺叶切除治疗早期肺癌的疗效及术后并发症的比较

Comparison of curative effect and postoperative complications between segmental and lobectomy in the treatment of early lung cancer

目的探讨肺段切除和肺叶切除治疗早期肺癌的疗效及术后并发症的比较。方法选取2020年1月~2021年1月我院收入早期肺癌患者102例,按照随机数字表法分为试验组(n=51)及对照组(n=51),试验组行肺段切除治疗,对照组行肺叶切除治疗,对比两组患者手术时间、术中出血量、住院时间差异,比较两组患者术前及术后1个月肺功能[1s用力呼气容积(FEV1)、用力肺活量(FVC)、每分钟最大通气量(MVV)]变化;对比术后并发症发生情况、1年无瘤生存期差异。结果试验组患者术中出血量、住院时间均小于对照组,差异具有统计学意义(P<0.05);两组手术时间比较,差异无统计学意义(P>0.05);试验组患者治疗后FEV1、FVC、MVV等肺功能指标均小于治疗前,且试验组大于对照组,差异具有统计学意义(P<0.05);两组患者术后并发症发生率比较,差异无统计学意义(P>0.05);两组术后1年无瘤生存期比较,差异无统计学意义(P>0.05)。结论早期肺癌患者应用肺段切除与肺叶切除均可延长生存时间,并发症少,安全可行,且肺段切除能够在保护患者肺功能方面更有效。

Objective To compare the efficacy and postoperative complications of segmental and lobectomy in the treat⁃ment of early lung cancer.Methods From January 2020 to January 2021,102 patients with early⁃stage lung cancer in our hospital were selected and divided into the test group(n=51)and the control group(n=51)according to the random num⁃ber table method.The test group was treated with segmental lung resection and the control group was treated with lobectomy,The changes of pulmonary function[1 s forced expiratory volume(FEV1),forced vital capacity(FVC)and maximum ventila⁃tion per minute(MVV)]were compared between the two groups before and one month after operation;The incidence of post⁃operative complications and 1⁃year tumor free survival were compared.Results the bleeding volume and hospitalization time in the experimental group were significantly lower than those in the control group(P<0.05);There was no significant difference in the operation time between the two groups(P>0.05);After treatment,FEV1,FVC,MVV and other pulmonary function indexes in the test group were lower than those before treatment,and the difference was statistically significant(P<0.05);There was no significant difference in the incidence of postoperative complications between the two groups(P>0.05);There was no significant difference in the 1⁃year tumor free survival between the two groups(P>0.05).Conclusion Both segmental resection and lobectomy can prolong the survival time of patients with early lung cancer,with fewer com⁃plications,safety and feasibility,and segmental resection can be more effective in protecting the lung function of patients.