光动力疗法联合牙周基础治疗种植体周围炎的疗效

Efficacy of Photodynamic Therapy Combined with Initial Periodontal Therapy for Peri-Implantitis

目的 系统评价光动力疗法联合牙周基础治疗种植体周围炎的疗效。方法 检索PubMed、Embase、Cochrane library、Web of Science等4个数据库,检索时限为从建库到2022年6月30日,搜集光动力疗法联合治疗种植体周围炎的随机对照研究,由2名评价员独立按照纳入与排除标准筛选文献、提取资料和评价质量后,采用RevMan5.3软件对符合纳入标准的研究进行Meta分析。结果 共检得636篇文献,最终纳入8项研究。Meta分析结果表明:光动力疗法联合牙周基础治疗可较好改善临床疗效。治疗3个月后的探诊出血、探诊深度、临床附着水平指数均优于对照组,差异有统计学意义(P<0.05);治疗6个月后的探诊出血、探诊深度、骨丧失指数均优于对照组,差异有统计学意义(P<0.05);治疗12个月后的骨丧失指数优于对照组,差异有统计学意义(P<0.05)。结论:光动力疗法联合牙周基础治疗种植体周围炎对探诊出血、探诊深度、骨丧失、临床附着水平等有更为明显的改善。

Objective To systematically review the efficacy of photodynamic therapy combined with initial periodontal therapy in the treatment of periodontitis.Methods PubMed,Embase,Cochrane Library,and Web of Science were searched from database inception to June 30,2022.The randomized controlled studies of photodynamic therapy combined with the treatment of periimplantitis were collected and evaluated by two participants.After the researchers independently screened the literature according to the inclusion and exclusion criteria,extracted the data and evaluated the quality,the RevMan5.3software was used to conduct a Meta-analysis of the studies that met the inclusion criteria.Results A total of 636articles were screened,resulting in 8included studies.Meta-analysis indicated that PDT combined with basic periodontal therapy improved clinical efficacy.After 3months,the intervention group exhibited superior outcomes in bleeding,probing depth,and clinical attachment level compared to controls(P<0.05).After 6months,bleeding,probing depth,and bone loss favored the intervention group(P<0.05).At 12months,bone loss was significantly reduced in the intervention group(P<0.05).Conclusions PDT combined with periodontal basic treatment for implant periodontitis significantly improves bleeding on probing,probing depth,bone loss,and clinical attachment level.