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黄酮类化合物治疗心脑血管疾病机制及其新型递送系统研究进展

RESEARCH PROGRESS ON THE MECHANISM OF FLAVONOIDS IN THE TREATMENT OF CARDIOVASCULAR ANG CEREBROVASCULAR DISEASES AND ITS NEW DELIVERY SYSTEM
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摘要 研究发现,黄酮类化合物可有效降低心脑血管疾病的发生。黄酮类化合物治疗心脑血管疾病的机制主要有清除自由基、调控抗炎因子、舒张血管等。近年来,对于黄酮类成分新型递送系统的研究受到了广大学者的关注。本文对黄酮类化合物治疗心脑血管疾病的相关机制进行了总结,并对其新型递送系统的研究进展情况进行了综述,以期为黄酮类化合物被更好地开发利用提供参考。 It has been found that flavonoids can effectively reduce the occurrence of cardiovascular and cerebrovascular diseases.The mechanism of flavonoids in the treatment of cardiovascular and cerebrovascular diseases mainly includes scav-enging free radicals,regulating anti-inflammatory factors and relaxing blood vessels.In recent years,the research on new deliv-ery system of flavonoids has attracted the attention of many scholars.In this paper,the related mechanisms of flavonoids in the treatment of cardiovascular and cerebrovascular diseases were summarized,and the research progress of its new delivery system was reviewed in order to provide reference for the better development and utilization of flavonoids.
作者 师嘉浩 王鑫晶 成日青 萨仁高娃 何琴芳 塔娜 齐和日玛 SHI Jiahao;WANG Xinjing;CHENG Riqing;Sarengaowa;HE Qinfang;TA Na;Qiherima(College of Pharmacy,Inner Mongolia Medical University,Hohhot 010059,China;Medical Innovation Center for Nationalities,Inner Mongolia Medical University,Hohhot 010059,China)
出处 《内蒙古医科大学学报》 2024年第1期84-90,共7页 Journal of Inner Mongolia Medical University
基金 内蒙古自治区自然科学基金项目(2020MS08129) 内蒙古医科大学善学人才培养计划项目(ZY0201030)。
关键词 黄酮类化合物 心脑血管疾病 作用机制 药物递送系统 flavonoid cardiovascular action mechanism mechanism of action drug delivery system
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