寻常型银屑病态靶辨治体系的构建

Construction of a state-target differentiation and treatment system for psoriasis vulgaris

传统中医辨证论治寻常型银屑病的疗效参差不齐,迫切需要创新治疗方法突破治疗瓶颈。本文借鉴仝小林院士提出的“态靶结合”辨治模式,通过现代医学诊断与中药药理研究,探索寻常型银屑病的精准治疗路径。强调玄府郁闭为寻常型银屑病共有发病机制,根据其自然演变过程,分为郁、壅、虚三态,并针对不同态的特点,制定相应的治疗策略。此外,本文详细讨论了寻常型银屑病常见症靶、标靶及靶药,为临床提供了具体的治疗方案。

The efficacy of traditional Chinese medicine(TCM)differentiation and treatment for psoriasis vulgaris varies widely,necessitating innovative therapeutic approaches to break through its treatment bottleneck.This article draws upon the"state-target combination"treatment model proposed by Academician Tong Xiaolin,exploring a precise treatment pathway for psoriasis vulgaris through modern medical diagnosis and pharmacological research of Chinese materia medica.It emphasizes that the occlusion of the mysterious orifices(Xuanfu Yubi)is a common pathogenesis in psoriasis vulgaris.Based on its natural evolution process,the disease is categorized into three states:congestion(Yu),obstruction(Yong),and deficiency(Xu),with specific treatment strategies developed for each state's characteristics.Moreover,this paper discusses in detail the common symptom targets,biochemical indicator targets,and target drugs for psoriasis vulgaris,in a bid to provide specific treatment plans for its clinical differentiation and treatment.