围绝经期综合征治疗中黄体酮、补佳乐联合电针对患者围绝经期改良评分、性激素水平的影响

Effects of progesterone,progynova combined with electroacupuncture on modified Kupperman index score and sex hormone levels in the treatment of perimenopausal syndrome

目的综合分析黄体酮、补佳乐联合电针治疗对围绝经期综合征患者围绝经期改良评分、性激素水平的影响。方法选取76例围绝经期综合征患者为研究对象,通过随机数表法分成两组,每组38例。对照组采用黄体酮、补佳乐治疗,研究组在对照组基础上采用电针治疗。比较两组患者的围绝经期改良(KI)评分与围绝经期生存质量(MENQOL)评分,并比较两组的性激素水平[雌二醇(E_(2))、促卵泡生成激素(FSH)、黄体生成素(LH)]。结果治疗后,研究组KI、MENQOL评分分别为(15.59±5.15)分、(20.14±5.17)分,均低于对照组的(19.86±5.87)分、(24.20±5.82)分(P<0.05)。治疗后,研究组FSH、LH水平均低于对照组,E_(2)水平高于对照组(P<0.05)。结论在围绝经期综合征治疗中采用黄体酮、补佳乐联合电针具有显著意义,能减轻患者机体症状,促进激素水平改善,有利于提高其生活质量,优化预后,值得广泛应用。

Objective To comprehensively analyze the effects of progesterone,progynova combined with electroacupuncture on modified Kupperman index score and sex hormone levels in patients with perimenopausal syndrome.Methods 76 patients with perimenopausal syndrome were selected as the study objects and were divided into two groups by random number table method,with 38 cases in each group.The control group was treated with progesterone and progynova,and the study group was treated with electroacupuncture on the basis of the control group.The modified Kupperman index(KI)score and menopause-specific quality of life(MENQOL)score were compared between the two groups,and the sex hormone levels[estradiol(E_(2)),follicle-stimulating hormone(FSH),luteinizing hormone(LH)]were compared between the two groups.Results After treatment,the KI and MENQOL scores in the study group were(15.59±5.15)points and(20.14±5.17)points,respectively,which were lower than(19.86±5.87)points and(24.20±5.82)points in the control group(P<0.05).After treatment,the FSH and LH levels in the study group were lower than those in the control group,and the E_(2)level was higher than that in the control group(P<0.05).Conclusion The use of progesterone,progynova combined with electroacupuncture in the treatment of perimenopausal syndrome has significant significance,which can reduce the symptoms of patients,promote the improvement of hormone levels,improve the quality of life and optimize the prognosis,and is worthy of wide application.