血清抗苗勒管激素及性激素检测在多囊卵巢综合征中的诊断价值

Diagnostic value of serum anti-Mullerian hormone and sex hormone detection in polycystic ovary syndrome

目的分析抗苗勒管激素(AMH)及性激素检测在多囊卵巢综合征(PCOS)中的诊断价值。方法选取PCOS患者80例为研究组,选取同一时期体检女性55例为对照组,采集研究对象肘部静脉血,按流程完成血清AMH及性激素检测。分析两组检测项目的差异,以ROC曲线分析各项目对PCOS的诊断效能。结果对照组促卵泡生成激素(FSH)水平为(5.46±1.23)IU/L,高于研究组的(6.13±1.54)IU/L,促黄体生成素(LH)、LH/FSH、AMH水平均低于研究组(P<0.05);两组雌二醇水平比较,差异无统计学意义(P>0.05)。ROC曲线显示:血清FSH、LH、LH/FSH、AMH及血清AMH对PCOS均具有诊断价值(P<0.05),血清AMH对PCOS的诊断效能高于血清FSH、LH、LH/FSH,二者联合检测对PCOS的诊断效能高于单一指标。结论血清AMH及性激素对PCOS均具有一定诊断价值,当二者联用时,可进一步提升PCOS的诊断效能。

Objective To analyze the diagnostic value of anti-Mullerian hormone(AMH)and sex hormone detection in polycystic ovary syndrome(PCOs).Methods 80 patients with PCOS were selected as the study group,in the same period,55 women were selected as the control group.Elbow venous blood was collected and serum AMH and sex hormone were detected according to the procedure.The differences between the two groups of detection items were analyzed,and the diagnostic efficiency of each item for PCOS was analyzed by ROC curve.Results The level of follicle-stimulating hormone(FSH)in the control group was(5.46±1.23)IU/L,which was higher than(6.13±1.54)IU/L in the study group,and the levels of luteinizing hormone(LH),LH/FSH and AMH were lower than those in the study group(P<0.05);there was no significant difference in estradiol levels between the two groups(P>0.05).ROC curve shows:Serum FSH,LH,LH/FSH,AMH and serum AMH had diagnostic value for PCOS(P<0.05),and the diagnostic efficacy of serum AMH for PCOS was higher than serum FSH,LH and LH/FSH,and the diagnostic efficacy of combined detection of both was higher than that of single index for PoS.Conclusion Serum AMH and sex hormone have certain diagnostic value for PCOS,and when they are combined,the diagnostic efficiency of PCOS can be furtherimproved.