期刊文献+

依诺肝素联合地屈孕酮治疗先兆流产的临床疗效 被引量:1

Clinical efficacy of enoxaparin combined with desdrogesterone in the treatment of threatened abortion
下载PDF
导出
摘要 目的观察依诺肝素联合地屈孕酮治疗先兆流产的临床疗效。方法选取80例先兆流产患者,根据随机数字表法分为研究组与对照组,各40例。对照组采用地屈孕酮进行治疗,研究组在对照组基础上联合依诺肝素进行治疗。比较两组临床疗效、临床症状缓解时间、血常规、凝血功能指标及足月妊娠情况。结果研究组总有效率为95.00%,高于对照组的77.50%,差异有统计学意义(P<0.05)。研究组阴道出血症状缓解时间、腹痛改善时间、腰酸改善时间均短于对照组,差异有统计学意义(P<0.05)。治疗后,两组血小板计数、D-二聚体、纤维蛋白原指标均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。研究组足月分娩率为95.00%,高于对照组的77.50%,差异有统计学意义(P<0.05)。结论对先兆流产患者实施依诺肝素联合地屈孕酮进行治疗,疗效显著,可有效改善血常规以及凝血功能指标,有效缩短临床症状改善时间,提升足月分娩率,值得临床推广。 Objective To observe the clinical efficacy of enoxaparin combined with desdrogesterone in the treatment of threatened abortion.Methods 80 patients with threatened abortion were selected and divided into study group and control group with 40 cases each according to random number table method.The control group was treated with desdrogesterone,and the study group was treated with enoxaparin sodium on the basis of the control group.The clinical efficacy,clinical symptom remission time,blood routine and coagulation function indexes,and full-term pregnancy were compared between the two groups.Results The total effective rate of the study group was 95.00%,which was higher than that of the control group(77.50%),the difference was statistically significant(P<0.05).The relief time of vaginal bleeding,abdominal pain improvement time and lumbar acid improvement time in the study group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the platelet count,D-dimer and fibrinogen indexes in 2 groups were lower than before treatment,and the study group was lower than the control group,the difference was statistically significant(P<0.05).The term delivery rate of the study group was 95.00%,higher than that of the control group(77.50%),the difference was statistically significant(P<0.05).Conclusion The treatment of enoxaparin combined with desdrogesterone in patients with threatened abortion has a significant effect,which can effectively improve blood routine and coagulation function indicators,effectively shorten the improvement time of clinical symptoms,and increase the rate of full-term delivery,which is worthy of clinical promotion.
作者 王颖 Wang Ying(Department of First Obstetrics,Chaoyang District Maternal and Child Health Hospital,Beijing 100025,China)
出处 《实用妇科内分泌电子杂志》 2024年第8期43-46,共4页 Electronic Journal of Practical Gynecological Endocrinology
关键词 先兆流产 依诺肝素 地屈孕酮 临床疗效 Threatened abortion Enoxaparin Dydrogestone Clinical effect
  • 引文网络
  • 相关文献

参考文献8

二级参考文献92

共引文献23

同被引文献9

引证文献1

;
使用帮助 返回顶部