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多组学技术在畜禽重要经济性状研究中的应用

Application of Multi-omics Technology in the Study of Important Economic Traits of Livestock and Poultry
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摘要 随着测序技术的发展,大量组学测序技术不断涌现并得以推广,产生了包括基因组、表观基因组、转录组、蛋白质组、代谢组、微生物组等大量的组学数据。这些数据对深入研究和揭示畜禽重要经济性状(生长性状、繁殖性状、肉质性状、抗病性状等)的复杂调控过程具有重要意义。仅通过单一层面的组学无法揭示畜禽重要经济性状的复杂性,而多组学技术可以系统解析畜禽重要经济性状的机理和表型,并逐渐成为研究畜禽重要经济性状的主要方法。本文综述了多组学技术的方法、优点及其在畜禽重要经济性状研究中的应用,旨在对畜禽重要经济性状的研究提供参考和思路。 With the development of sequencing technology,a large number of omics sequencing technologies continue to emerge and promote,resulting in a large number of omics data including genome,epigenome,transcriptome,proteome,metabolome,microbiome and so on.These data are of great significance for in-depth study and revelation of the complex regulatory process of important economic traits(growth traits,reproductive traits,meat traits,disease resistance traits,etc.)of livestock and poultry.The complexity of important economic traits of livestock and poultry can not be revealed through a single level of omics alone,while multi-omics technology can systematically analyze the mechanism and phenotype of important economic traits of livestock and poultry,thus gradually become the main method for studying important economic traits of livestock and poultry.This article reviews the methods,advantages and application of multi-omics techniques in the study of important economic traits of livestock and poultry,aiming to provide references and ideas for the study of important economic traits of livestock and poultry.
作者 王亚鑫 王璟 田学凯 杨公社 于太永 WANG Yaxin;WANG Jing;TIAN Xuekai;YANG Gongshe;YU Taiyong(Laboratory of Animal Fat Deposition and Muscle Development,Key Laboratory of Animal Genetics,Breeding and Reproduction of Shaanxi Province,College of Animal Science and Technology,Northwest A&F University,Yangling 712100,China;Institute of Animal Husbandry and Veterinary Medicine,Henan Academy of Agricultural Sciences,Zhengzhou 450000,China)
出处 《畜牧兽医学报》 CAS CSCD 北大核心 2024年第5期1842-1853,共12页 ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金 国家重点研发计划项目(2021YFD1301205) 陕西省畜禽育种“两链”融合重点专项(2022GD-TSLD-46)。
关键词 畜禽 多组学技术 经济性状 livestock and poultry multi-omics techniques economic traits
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