胸腔镜肺癌手术治疗老年非小细胞肺癌的临床效果分析

Clinical Effect Analysis of Thoracoscopic Lung Cancer Surgery in the Treatment of Elderly Non-Small Cell Lung Cancer

目的:分析胸腔镜肺癌手术治疗老年非小细胞肺癌的临床效果。方法:选取2022年3月—2023年4月宣威市第一人民医院收治的老年非小细胞肺癌患者60例作为研究对象,采用随机数字表法分为对照组和观察组,各30例。对照组采用常规开胸肺癌根治术,观察组采用胸腔镜肺癌手术。比较两组治疗效果、术中指标、术后指标、炎性因子水平、术后并发症发生情况。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P=0.038)。观察组手术时间、引流管留置时间、住院时间短于对照组,术中出血量、术后引流量、止痛药用量少于对照组,差异有统计学意义(P<0.001)。治疗前,两组白细胞介素-6(IL-6)、C反应蛋白(CRP)和肿瘤坏死因子-α(TNF-α)水平比较,差异无统计学意义(P>0.05);治疗后,两组IL-6、CRP、TNF-α水平升高,观察组低于对照组,差异有统计学意义(P<0.05)。观察组术后并发症总发生率低于对照组,差异有统计学意义(P=0.038)。结论:胸腔镜肺癌手术治疗老年非小细胞肺癌的临床效果显著,可改善术中指标、术后指标,且炎性因子水平与术后并发症发生率低于常规开胸肺癌根治术。

Objective:To analyze the clinical effect of thoracoscopic lung cancer in the treatment of elderly non-small cell lung cancer.Methods:A total of 60 elderly patients with non-small cell lung cancer were selected as the research objects at the First People's Hospital of Xuanwei City from March 2022 to April 2023,and were divided into control group and observation group by random number table method,with 30 cases in each group.The control group underwent routine thoracoscopic radical operation for lung cancer,and the observation group underwent thoracoscopic surgery for lung cancer.The therapeutic effect,intraoperative index,postoperative index,inflammatory factor level and postoperative complications were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P=0.038).The operation time,drainage tube retention time and hospital stay in the observation group were shorter than those in the control group,and the intraoperative blood loss,postoperative drainage volume and dosage of painkillers were less than those in the control group,the differences were statistically significant(P<0.001).Before treatment,there was no significant difference in the levels of interleukin-6(IL-6),C-reactive protein(CRP)and tumor necrosis factor-α(TNF-α)between the two groups(P>0.05).After treatment,the levels of IL-6,CRP and TNF-αwere increased in both groups,but the observation group was lower than the control group,the difference was statistically significant(P<0.05).The incidence of postoperative complications in the observation group was lower than that in the control group,and the difference was statistically significant(P=0.038).Conclusion:Thoracoscopic lung cancer surgery has significant clinical effects in the treatment of elderly non-small cell lung cancer,which can improve intraoperative and postoperative indexes,and the level of inflammatory factors and the incidence of postoperative complications are lower than that of conventional thoracotomy radical lung cancer.