不同血液净化方式对维持性血液透析患者的治疗效果观察

Effect of Different Blood Purification Methods on Maintenance Hemodialysis Patients

目的:探讨不同血液净化方式对维持性血液透析患者治疗效果及生活质量的影响。方法:选取宁夏回族自治区中医医院暨中医研究院2018年1月—2022年12月收治的96例维持性血液透析患者为研究对象,经随机数字表法分为对照组和研究组。对照组采用常规血液透析,研究组采用血液灌流联合常规血液透析。比较两组炎性因子水平、治疗效果及生活质量情况。结果:研究组治疗后白细胞介素-2、白细胞介素-6、白细胞介素-1β、白细胞介素-8、肿瘤坏死因子-α、C反应蛋白水平低于对照组,差异有统计学意义(P<0.05)。研究组患者治疗总有效率为95.83%(46/48),高于对照组的83.33%(40/48),差异有统计学意义(P<0.05)。研究组患者治疗后屈服、回避评分低于对照组,面对评分高于对照组,差异有统计学意义(P<0.05)。结论:维持性血液透析患者采取血液灌流联合常规血液透析治疗,疗效显著,有助于提高患者生活质量。

Objective:To explore the influence of different blood purification methods on the treatment effect and quality of life of maintenance hemodialysis patients.Methods:Ninety-six patients with maintenance hemodialysis admitted to Ningxia Hui Autonomous Region Hospital and Academy of Traditional Chinese Medicine from January 2018 to December 2022 were selected as the study objects,and were divided into control group and study group by random number table method.The control group was treated with routine hemodialysis,and the study group was treated with hemoperfusion combined with routine hemodialysis.The levels of inflammatory factors,therapeutic effect and quality of life were compared between the two groups.Results:The levels of interleukin-2,interleukin-6,interleukin-1β,interleukin-8,tumor necrosis factor-αand C-reactive protein in the study group after treatment were lower than those in the control group,and the differences were statistically significant(P<0.05);The total effective rate of the study group was 95.83%(46/48),which was higher than that of the control group 83.33%(40/48),the difference was statistically significant(P<0.05);after treatment,the yield and avoidance scores in the study group were lower than those in the control group,and the face scores were higher than those in the control group,with statistical significance(P<0.05).Conclusion:Patients with maintenance hemodialysis were treated with hemoperfusion combined with routine hemodialysis,which was effective and helpful to improve the quality of life of patients.