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凝血功能相关指标检测在胆囊癌患者中的评估价值

The evaluation value of coagulation function-related index detection in patients with gallbladder cancer
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摘要 目的:探讨凝血功能相关指标检测在胆囊癌患者中的评估价值。方法:选取2021年10月至2023年1月我院收治的胆囊癌患者60例作为观察组,并选取同期我院收治的50例胆囊炎患者作为对照组,使用全自动凝血分析仪对所有患者凝血功能指标进行检测,比较胆囊癌组和胆囊炎组凝血功能指标,统计胆囊癌患者分化程度,对中低分化程度和高分化程度凝血功能指标进行比较,并对不同临床分期胆囊癌患者凝血功能指标进行比较。结果:相比于对照组,观察组患者PT和Fib水平更高(P<0.05);观察组患者aPTT水平低于对照组(P<0.05)。60例胆囊癌患者中,中低分化和高分化患者各36例和24例。中低分化组患者Fib水平低于高分化组(P<0.05)。60例胆囊癌患者中,TNMⅠ-Ⅱ期患者39例,TNMⅢ-Ⅳ期患者21例。两组患者PT和aPTT水平差异无统计学意义(P>0.05);TNMⅠ-Ⅱ期患者Fib水平低于TNMⅢ-Ⅳ期,差异有统计学意义(P<0.05)。结论:胆囊癌患者凝血功能指标存在明显异常,可评估患者病情状况,对患者预后提供一定的参考价值。
作者 陈建丽 叶峰山 宋育明 聂力平 CHEN Jianli;YE Fengshan;SONG Yuming;NIE Liping
出处 《甘肃医药》 2024年第5期417-418,427,共3页 Gansu Medical Journal
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