线粒体转移在缺血性卒中中的研究进展

Research progress on mitochondrial transfer in the pathogenesis of ischemic stroke

缺血性卒中的流行病学表现为发病率高、致死致残率高及复发率高,但目前的临床治疗方法仍存在局限性。缺血性卒中的发生与线粒体转移密切相关。线粒体在细胞能量供应、信号传递等方面至关重要。近年来,将线粒体转移应用在缺血性卒中治疗的相关研究已经取得了进展。作者综述了目前缺血性卒中发生后线粒体转移的相关研究,以期通过分析当下研究的不足并进行展望,为缺血性卒中临床治疗新方法的研究提供指引性帮助。

The epidemiology of ischemic stroke is characterized by a high incidence,high mortality and disability rates,and a high recurrence rate,yet current clinical treatment methods are limited.The onset of ischemic stroke is closely related to mitochondrial transfer.Mitochondria plays a crucial role in cellular energy supply,signal transmission,and other functions.In recent years,research on the application of mitochondrial transfer in the treatment of ischemic stroke has made progress.The authors reviewed the current research progress on mitochondrial transfer following ischemic stroke,aiming to highlight the existing research gaps and future prospects.This review provides guidance for the development of new clinical treatment methods for ischemic stroke.