慢性肾衰竭风险预测模型构建的研究进展

Advances in the construction of risk prediction models for chronic kidney failure

慢性肾脏疾病(CKD)为全球主要的公共健康问题。当CKD进展到肾功能衰竭时,患者需要选择肾脏替代治疗(KRT)或保守治疗(姑息治疗或非透析治疗)。近年来有关慢性肾功能衰竭风险预测模型的研究不断发展,这些模型通过人口学指标、临床指标和实验室数据等来预测CKD进展到肾功能衰竭并且需要KRT的可能性。本文将详细阐述CKD进展到慢性肾衰竭的风险预测模型研究进展,希望有助于慢性肾衰竭预防策略的制定。

Chronic kidney disease(CKD)is a major public health problem worldwide.When CKD patients progress to the stage of kidney failure,kidney replacement therapy(KRT)or conservative treatment(palliative or non-dialysis treatment)will be needed.The risk prediction models of chronic kidney failure have been developed in recent years.These models,focusing on demographic indicators,clinical indicators,and laboratory data,are used to predict the likelihood of progression to kidney failure and requiring KRT.This article will retrieve prediction models for chronic kidney failure as an outcome,demonstrate the current research progress,and hope that it may be helpful for the strategies of preventing chronic kidney failure.