癫痫性猝死的病理学研究进展

Pathological research progress of sudden unexpected death in epilepsy

癫痫性猝死(SUDEP)是指癫痫患者突发、意料之外且原因不明的死亡,是癫痫患者死亡风险显著增高的重要原因。由SUDEP所致的癫痫突发死亡已成为重大的公共卫生问题。随着尸检病例的积累和病理学研究的发展,SUDEP的病理学亦有一些新的发现。通过检索相关文献,现就SUDEP的病理学研究进展做一综述。

Sudden unexpected death in epilepsy(SUDEP)refers to the sudden,unexpected and unexplained death of epilepsy patients,which is an important reason for the significant increase of the death risk of epilepsy patients.The risk factors of SUDEP are related to poor control of seizures,nocturnal seizures,prone position,antiepileptic drugs,comorbidity,etc.Epilepsy death caused by SUDEP has become a major public health problem.The latest progress in neuropathology and cardiopulmonary pathology of SUDEP was reviewed in this article.