智能控压输尿管软镜吸引取石术治疗2~3cm肾结石的临床研究

Clinical study on the treatment of 2-3cm renal stones with intelligent pressure controlled retrograde nephrolithotomy

目的探讨智能控压输尿管软镜吸引取石术(intelligent pressure controlled retrograde renal surgery,IRIRS)治疗长径2~3cm肾结石的临床疗效和安全性。方法将2019年1月至2021年12月赣州市人民医院收治的110例长径2~3cm肾结石患者采用随机数字表法分为IRIRS组和对照组(微通道经皮肾镜吸引取石术),每组55例,比较两组间的手术时间、术后4周结石清除率、血红蛋白下降值、术后疼痛评分、住院时间、及并发症情况。结果IRIRS组和对照组的手术时间、术后4周的结石清除率比较,差异无统计学意义(P>0.05);IRIRS组住院时间、血红蛋白下降值、术后疼痛评分均低于对照组(P<0.05);IRIRS组和对照组术后总并发症发生率差异无统计学意义(P>0.05)。结论IRIRS是治疗长径2~3cm肾结石有效、安全的方法,值得临床推广应用。

Objective To investigate the clinical efficacy and safety of intelligent pressure controlled retrograde renal surgery(IRIRS)for the treatment of 2-3cm kidney stones.Methods Totally 110 patients with renal stones with a diameter of 2-3cm admitted to Ganzhou People’s Hospital from January 2019 to December 2021 were randomly divided into IRIRS group and control group(microchannel percutaneous nephrolithotomy with vacuum aspiration),with 55 cases in each group.The surgical time,rate of stone clearance,hemoglobin decrease,scores for postoperative pain,hospital stay and incidence of complications were systematically compared between the two groups.Results The surgical time and stone clearance rates at four weeks post-operation did not exhibit any statistically significant differences between the IRIRS group and the control group(P>0.05).The hospitalization time,hemoglobin decrease,and scores for postoperative pain in the IRIRS group were notably lower compared to the control group,with these differences being statistically significant(P<0.05).The difference in total postoperative complication rates between the IRIRS and control groups was not statistically significant(P>0.05).Conclusion IRIRS is an effective and safe method for treating renal stones with a diameter of 2-3 cm,meriting broader clinical adoption and application.