子宫内膜癌早期检测方法研究现状

Research status of early detection methods for endometrial carcinoma

子宫内膜癌(EC)是女性常见的妇科恶性肿瘤之一,近年来发病率和死亡率不断上升,且趋于年轻化。早期诊断EC可改善患者的远期预后,目前对于EC的早期检测还没有达成共识。本文对早期包括子宫内膜组织活检、子宫内膜取样器、宫腔镜、宫腔灌洗液等子宫腔内检测方法,以及影像学、外周血的相关指标、DNA甲基化等子宫腔外检测方法的优劣势进行综述。

Endometrial carcinoma(EC)is one of the most common gynecological malignancies in women.In recent years,the incidence and mortality rates of EC have been steadily increasing,and the trend is towards a younger age at onset.Early diagnosis of EC can improve long-term prognosis for patients,but consensus on early detection methods for EC has not yet been reached.This article reviews the advantages and disadvantages of early intrauterine detection methods such as endometrial tissue biopsy,endometrial uterine sampling devices,hysteroscopy,and uterine lavage fluid,as well as early extrauterine detection methods such as imaging,peripheral blood related indicators,and DNA methylation.