预测健康成年人标准肝脾体积的新公式

A new formula for predicting standard liver and spleen volume in healthy adults

目的为解决当前测量肝脾体积费时费力的问题,建立健康成人肝脾体积计算公式,以望为在肝硬化患者中的应用提供理论支持。方法采用CT检查方法计算了305名符合纳排标准健康成年人的肝脾体积,记录其性别、年龄、身高(BH)、体重(BW)、体表面积(BSA)、体质指数(BMI),进行Pearson相关性分析和逐步多元线性回归分析,分析各参数与肝脾体积的相关性,并建立肝脾体积计算公式。最后,将建立的肝脏体积计算公式与现有公式的结果进行比较。结果CT测量的肝脏体积(CTLV)和CT测量的脾脏体积(CTSV)分别为(1043.18±244.60)cm^(3)和(175.07±88.15)cm^(3)。年龄、BH、BW、BSA及BMI与CTLV、CTSV显著相关(P<0.01)。BSA与CTLV和CTSV的相关性最强(P<0.001)。基于这些结果,建立了计算标准肝脾体积的新公式。结论将建立的肝脏体积公式与现有公式进行比较,发现所建立的肝脏体积计算公式具有更高的准确性以及更低的误差,脾脏体积计算公式的准确性较好。

Objective In order to solve the problem of time-consuming and laborious measurement of liver and spleen volume,a formula for calculating the volume of liver and spleen in healthy adults is established to provide theoretical support for the application in patients with cirrhosis.Methods The liver and spleen volume of 305 healthy adults who met the inclusion and exclusion criteria were calculated by CT examination.Their gender,age,body height(BH),body weight(BW),body surface area(BSA)and body mass index(BMI)were recorded.Pearson correlation analysis and stepwise multiple linear regression analysis were performed to analyze the correlation between each parameter and liver and spleen volume,and to establish a formula for calculating liver and spleen volume.Finally,the results of the established liver volume calculation formula was compared with the existing formula.Results The liver volume calculated by CT(CTLV)and spleen volume calculated by CT(CTSV)were(1043.18±244.60)cm^(3) and(175.07±88.15)cm^(3),respectively.The age,BH,BW,BSA and BMI were significantly correlated with CTLV and CTSV(P<0.01).BSA had the strongest correlation with CTLV and CTSV(P<0.001).Based on these results,a new formula for calculating the standard liver and spleen volume was established.Conclusion Comparing the established liver volume formula with the existing formula,it is found that the established liver volume calculation formula has higher accuracy and lower error,and the accuracy of the spleen volume calculation formula is better.