太极拳对卒中后抑郁的作用机制研究进展

A review of the research progress on the mechanisms of Tai Chi on post-stroke depression

太极拳可以通过影响神经内分泌、氧化应激、免疫炎症反应,调节脑源性神经营养因子及单胺类神经递质水平影响卒中后脑损伤及神经恢复,并可作用于卒中后抑郁相关危险因素从而影响卒中后抑郁的发病和预后,但相关临床及机制研究相对不足,缺少循证支持,需要更多大样本随机对照临床研究以及疗效循证评价。

Tai Chi can affect brain injury and neurological recovery after stroke by affecting neuroendocrine,oxidative stress and immune inflammatory response and regulating the level of brain-derived neurotrophic factors and monoamine neurotransmitters,and it can also affect the incidence and prognosis of post-stroke depression by acting on the related risk factors,however,it is relatively insufficient in clinical research and mechanism exploration and evidence-based support is deficient.More larger sample randomized controlled clinical trials and evidence-based evaluation of efficacy are needed.