基于MCM41掺杂的萘普生印迹整体柱的制备及研究

Preparation and Study of Naproxen Imprinted Monolithic Columns based on MCM41 Doping

本研究通过分子印迹技术以原位聚合法成功合成了MCM41-MPS掺杂的萘普生印迹整体柱。通过改进配方进而考察色谱条件,实现印迹因子最高达10.7,相比未掺杂MCM41-MPS的印迹整体柱,印迹因子提高两倍多。结果表明,MCM41-MPSMIP比MIP具有更高的保留因子和印迹因子,并通过傅立叶红外吸收光谱(FT-IR)和扫描电子显微镜(SEM)对聚合物进行表征,采用Langmuir拟合得到MCM41-MPS MIP的最大吸附量为10.89 mg/g,最终,对湖水中加标的萘普生进行固相萃取,回收率达96.40%。

In this study,MCM41-MPS-doped naproxen imprinted monolithic columns were successfully synthesized by molecularly imprinted technique with in situ polymerization.By improving the formulation and then examining the chromatographic conditions,an imprint factor of up to 10.7 was achieved,which was more than two times higher than that of the undoped MCM41-MPS imprinted monolithic column.The results showed that MCM41-MPS MIP had higher retention and blotting factors than MIP,and the polymer was characterized by Fourier infrared absorption spectroscopy(FT-IR)and scanning electron microscopy(SEM),and the maximum adsorption amount of MCM41-MPS MIP was obtained to be 10.89 mg/g by using Langmuir fitting,and ultimately,the spiked lake water was spiked with naproxen was subjected to solid phase extraction with a recovery of 96.40%.