新生儿败血症的临床管理进展

Advances in clinical management of neonatal sepsis

新生儿败血症是新生儿各类合并症和不良预后的重要原因。国内外新生儿败血症的疾病负担仍较为严重。产时抗生素预防策略、早发型败血症风险计算器的应用和新生儿病房的质量改进等管理方案均有利于减轻新生儿败血症的疾病负担。该文就新生儿败血症的流行病学、危险因素和临床管理进展进行综述。

Neonatal sepsis,as a significant cause of various complications and adverse outcomes in neonates,remains a serious health burden both domestically and internationally.Strategies such as antibiotic prophylaxis during delivery,the utilization of early-onset sepsis risk calculators,and quality improvement initiatives in neonatal wards are beneficial in alleviating the disease burden of neonatal sepsis.This paper provides a review of the epidemiology,risk factors,and recent advances in clinical management of neonatal sepsis.