经皮穴位电刺激改善功能性消化不良患者胃肌电活动效果的研究

Effect of percutaneous acupoint electrical stimulation on improving gastric myoelectric activity in patients with functional dyspepsia

目的探讨经皮穴位电刺激(TEAS)对功能性消化不良(FD)患者胃电活动的影响。方法选取2022年4月至2024年2月在合肥市第二人民医院就诊的60例FD患者,采用随机数字表法分为单一治疗组(曲美布汀,30例)和联合治疗组(经皮穴位电刺激联合曲美布汀,30例),分别于空腹和餐后检测2组患者的胃电图(EGG),分析胃电图主要参数的变化,同时研究治疗后2组症状改善情况。结果与单一治疗组比较,联合治疗组的餐前及餐后正常慢波比例较高(P<0.001),联合治疗组的餐后紊乱系数较低(P<0.001),联合治疗组的餐前及餐后主频率较高(P<0.001),联合治疗组的餐后餐前功率比较高(P<0.001);治疗后2组患者症状严重程度评分都降低,且联合治疗组的临床症状严重程度评分较低,差异有统计学意义(P<0.001)。结论经皮穴位电刺激可以调节胃动力,改善FD患者的胃肌电活动,促进胃排空,从而改善FD患者的临床症状。

Objective To investigate the effects of TEAS on gastric electrical activity in patients with functional dyspepsia(FD).Methods A total of 60 FD patients admitted to the Second People′s Hospital of Hefei from April 2022 to February 2024 were selected and divided into single treatment group(30 cases)and combined treatment group(30 cases)with percutaneous acupoint electrical stimulation combined with trimebutin)by random number table.The electrogastrogram(EGG)of the two groups were detected on fasting and postprandial respectively.The main parameters of electrogastrogram were compared and analyzed.At the same time,the effect of symptom improvement in 2 groups after treatment was studied.Results Compared with the single treatment group,the proportion of normal slow wave before and after meals was higher in the combined treatment group(P<0.001),the coefficient of postprandial disturbance was lower in the combined treatment group(P<0.001),the main frequency before and after meals was higher in the combined treatment group(P<0.001),and the power before and after meals was higher in the combined treatment group(P<0.001).Symptom severity scores in both groups decreased after treatment,and clinical symptom severity scores in the combined treatment group were lower,the difference was statistically significant(P<0.001).Conclusions Percutaneous acupoint electrical stimulation can regulate gastrointestinal motility,improve gastric myoelectric activity and gastric emptying in FD patients,and thus improve clinical symptoms in FD patients.