非酒精性脂肪性肝病中医治疗研究进展

Research progress on traditional Chinese medicine treatment of nonalcoholic fatty liver disease

非酒精性脂肪性肝病(NAFLD)通常表现为没有过度饮酒史,并排除其他明确的肝病,是一种在临床普遍存在的代谢综合征。该疾病的发生主要归因于饮食结构和生活方式等因素,饮食不当、缺乏运动、肥胖、糖尿病、高血压等多种因素易引起肝细胞内脂肪堆积从而导致肝脏损伤,发为本病。现代医学尚未研制出特效药物,治疗上目前主要以保肝调脂降酶及防治并发症为主,而中医提倡整体观念,强调辨证论治,以达到为患者提供更加全面的治疗方案,具有全方位、多靶点、安全性高等优点,能够有效防治NAFLD。本文通过查阅近年来的相关文献和研究成果,介绍中医治疗进展,为临床治疗或进一步研究提供参考依据。

Nonalcoholic fatty liver disease(NAFLD)is a metabolic syndrome that is common in clinical practice.It is usually characterized by no history of excessive drinking and excludes other clear liver diseases.The occurrence of this disease is mainly attributed to factors such as dietary structure and lifestyle.Improper diet,lack of exercise,obesity,diabetes,hypertension and other factors can easily cause fat accumulation in liver cells,resulting in liver damage and eventually leading to the development of NAFLD.As of right now,modern medicine has no effective medication to treat NAFLD.At present,the treatment is mainly based on liver protection,lipid regulation,enzyme reduction and prevention and treatment of complications.Traditional Chinese medicine(TCM)advocates the concept of holism,emphasizes syndrome differentiation and treatment,so as to provide patients with a more comprehensive therapeutic schedule.It has the advantages of omni-directional therapy,multi-target and high safety,and can effectively prevent and treat NAFLD.By consulting the relevant literature and research results in recent years,this paper hopes to provide reference for clinical treatment or further research by reviewing these contents.