轻同位素分离纯化与催化标记研究进展

Advances in light isotopes separation and catalytic labeling

氢碳氮氧等稳定轻同位素广泛应用于医疗药物、临床诊断、环境地质等领域。如何获得高纯同位素原料并将其标记到目标化合物是同位素产业的核心技术。基于量子效应的同位素吸附分离方法具有选择性高、能耗低等优势,在同位素分离纯化方面展现出应用潜力;而催化同位素交换法和官能团转化法是制备同位素标记化合物的重要手段。基于量子效应的同位素分离与催化标记技术的核心之一是开发高效吸附及催化材料。总结了同位素分离及标记的最新进展,分析了核心材料的发展现状与性能强化方法,并对轻同位素分离纯化及标记方面的挑战和发展趋势进行了展望。

Stable light isotopes such as hydrogen,carbon,nitrogen and oxygen are widely used in medical drugs,clinical diagnosis,environmental geology and other fields.The enrichment of high-purity isotopes as raw materials to obtain targeted isotope-labeled compounds are core technology for isotope application.Adsorption separation based on quantum effect displays low energy footprint and high efficiency and thus is considered as a promising method for the purification of isotope gases.Catalytic isotope exchange and functional group conversion reactions are important technologies for isotope labeling.The key for both processes is the development of efficient adsorbents and catalysts.This paper summarizes the recent research progress for isotopes separation and catalytic labeling.Then,the development status of key materials is analyzed along with the strategy for performance optimization.Finally,the research challenges and developing trends in this field are prospected.