《中国大动脉炎诊疗指南(2023)》要点解读

Interpretation on the Chinese Guideline for the Diagnosis and Treatment of Takayasus Arteritis(2023)

大动脉炎(Takayasu's arteritis, TAK)是一种累及主动脉及其一级分支的慢性大血管炎,可造成受累血管所供应脏器的缺血改变与功能障碍。为提高我国TAK的诊治水平,由国家皮肤与免疫疾病临床医学研究中心牵头组织,基于最新循证医学证据,结合我国临床实际,制定了以临床问题为导向的中国TAK诊治指南。该指南针对TAK诊治中的11个重要问题作出推荐,涵盖疾病诊断、病情评估、治疗原则、用药方案、抗栓管理、外科干预、围妊娠期管理等方面,旨在提升我国TAK的诊治水平,改善TAK患者的预后。本文对该指南的重要内容进行解读,以期促进指南在临床实践中的应用。

Takayasus arteritis(TAK)is a chronic large vessel vasculitis that involves the aorta and its primary branch arteries,which can result in limb ischemia and organ damage.A clinical practice guideline has been newly developed under the leadership of the National Clinical Medical Research Center for Dermatologic and Immunologic Diseases.This guideline provides evidence-based recommendations on 11 key issues in the management of TAK,covering the diagnosis,clinical evaluation,medical treatment,antithrombotic therapy,surgical intervention as well as pregnancy,and aims to guide the diagnosis and treatment of TAK in clinical practice and improve the outcomes of patients in China.This article interprets the key points of this guideline,in order to promote its application.