高通量血液透析治疗慢性肾功能衰竭的效果分析

Analysis of the Effect of High-flux Hemodialysis in the Treatment of Chronic Renal Failure

目的:分析高通量血液透析治疗慢性肾功能衰竭的效果。方法:选取2019年1月—2021年12月清镇市第一人民医院收治的慢性肾功能衰竭患者60例作为研究对象,随机分为常规组与试验组,各30例。常规组采用低通量血液透析,试验组采用高通量血液透析。比较两组肾功能指标、心血管并发症发生率、6个月存活率。结果:治疗前,两组血肌酐、血尿素氮、血红蛋白、白蛋白、尿素清除指数水平比较,差异无统计学意义(P>0.05);治疗后,两组血肌酐、血尿素氮、白蛋白水平低于治疗前,血红蛋白、尿素清除指数高于治疗前,试验组血肌酐、血尿素氮、白蛋白水平低于常规组,血红蛋白、尿素清除指数高于常规组,差异有统计学意义(P<0.05)。试验组心血管并发症发生率低于常规组,差异有统计学意义(P=0.037)。两组存活率比较,差异无统计学意义(P>0.05)。结论:高通量血液透析能够改善慢性肾功能衰竭患者肾功能指标,降低心血管并发症发生风险,安全性高。

Objective:To analyze the effect of high-flux hemodialysis in treating chronic renal failure.Methods:Sixty patients with chronic renal failure admitted to Qingzhen First People's Hospital from January 2019 to December 2021 were selected as the study subjects and randomly divided into the conventional group and the experimental group,each with thirty cases.The conventional group used low-flux hemodialysis,and the experimental group used high-flux hemodialysis.The renal function indexes,cardiovascular complication rate,and 6-month survival rate of the two groups were compared.Results:Before treatment,the levels of blood creatinine,blood urea nitrogen,hemoglobin,albumin,and urea clearance index were compared between the two groups,and the differences were not statistically significant(P>0.05);after treatment,the levels of blood creatinine,blood urea nitrogen and albumin in the two groups were lower than those before treatment,and the levels of hemoglobin and urea clearance index were higher than those before treatment;the levels of blood creatinine,blood urea nitrogen and albumin in the experimental group were lower than those in the conventional group,and the levels of hemoglobin and urea clearance index were higher than those in the conventional group,and the difference was statistically significant(P<0.05).The incidence of cardiovascular complications in the experimental group was lower than that in the conventional group,and the difference was statistically significant(P=0.037).The difference was not statistically significant when comparing the survival rates of the two groups(P>0.05).Conclusion:High-flux hemodialysis can improve the renal function indexes of chronic renal failure patients,reduce the risk of cardiovascular complications,which is safe.