聚六亚甲基双胍盐酸盐消毒剂长效消毒效果评价的试验研究

Experimental study on the evaluation of long-acting disinfection effect of polyhexamethylene biguanide hydrochloride disinfectant

目的评价聚六亚甲基双胍盐酸盐消毒剂的长效消毒效果,为我国消毒剂长效消毒效果评价方法的建立提供参考依据。方法参考英国标准PAS 2424的评价方法,观察不同浓度消毒剂样品对细菌繁殖体及致病性酵母菌的杀灭效果。结果此消毒剂样品对于大肠埃希菌的长效消毒效果最好,对于金黄色葡萄球菌和铜绿假单胞菌的长效消毒效果次之,对于白念珠菌的长效消毒效果最差,差异具有统计学意义(P<0.05)。结论聚六亚甲基双胍盐酸盐消毒剂样品对于大肠埃希菌和金黄色葡萄球菌具有24 h长效消毒效果。

Objective To evaluate the long-acting disinfection effect of polyhexamethylene biguanide hydrochloride disinfectant,and to provide a reference basis for the establishment of evaluation method for the long-acting disinfection effect of disinfectants in China.Methods Referring to the evaluation method of British standard PAS 2424,the killing effect of disinfectant samples with different concentrations on bacterial propagules and pathogenic yeasts was observed.Results This disinfectant sample had the best long-acting disinfection effect on Escherichia coli,followed by the long-acting disinfection effect on Staphylococcus aureus and Pseudomonas aeruginosa,and the worst long-acting disinfection effect on Candida albicans,and the difference was statistically significant(P<0.05).Conclusion The polyhexamethylene biguanide hydrochloride disinfectant sample has a 24 h long-acting disinfection effect on Escherichia coli and Staphylococcus aureus.