烧伤重症监护病房住院患者多重耐药菌感染及其危险因素分析

Analysis of multidrug-resistant organism infection and its risk factors in patients hospitalized in burn intensive care unit

目的了解烧伤重症监护病房(ICU)住院患者多重耐药菌(MDRO)感染及其危险因素。方法通过回顾性分析方法,对某医院烧伤ICU住院患者MDRO感染病原学特点和危险因素进行调查与分析。结果共调查住院患者139例,其中MDRO感染31例、84例次,MDRO感染率22.30%、例次率感染为60.43%。MDRO以金黄色葡萄球菌和鲍曼不动杆菌为主,构成比分别为45.24%和28.57%。MDRO主要分离自创面分泌物和痰液,构成比分别为59.52%和19.05%。多因素分析显示,手术≥2次、中心静脉置管和尿道插管留置是MDRO感染独立危险因素。结论烧伤ICU内MDRO感染以金黄色葡萄球菌和鲍曼不动杆菌为主,危险因素明确,应有针性地提出有效防控措施。

Objective To understand multidrug-resistant organism(MDRO)infection and its risk factors in patients hospitalized in burn intensive care unit(ICU).Methods Retrospective study was used to investigate and analyze the etiological characteristics and risk factors of MDRO infection in the burn ICU of a hospital.Results A total of 139 inpatients were investigated,including 31 cases and 84 times of MDRO infection.The MDRO infection rate was 22.30%and the infection case rate was 60.43%.MDRO was dominated by Staphylococcus aureus and Acinetobacter baumannii,with constituent ratios of 45.24%and 28.57%respectively.MDROs were mainly separated from wound secretions and sputum,with the constituent ratios of 59.52%and 19.05%respectively.Multivariate analysis showed that≥2 times of surgeries,central venous catheterization and urethral catheterization were independent risk factors for MDRO infection.Conclusion MDRO infections in burn ICU are mainly caused by Staphylococcus aureus and Acinetobacter baumannii.The risk factors are clear and effective prevention and control measures should be proposed.