早产儿视网膜病变退行组和治疗组影响因素分析

The analysis of the influence factors between the regress team and the therapy team among the ROP babies

目的分析早产儿视网膜病变退行组和治疗组的影响因素,以期对临床有一定帮助。方法收集2014年1月1日至2017年12月30日4年间在我院受检的早产儿4360例。比较退行组和治疗组的出生体重、出生孕周、诊断时间、吸氧时间和吸氧浓度;分析出生体重和出生孕周的相关性;比较两组出生体重和出生孕周的斜率。结果ROP患儿414例,退行组326例,治疗组88例。退行组和治疗组的出生孕周、出生体重、诊断时间经独立样本t检验,差异有统计学意义(均P=0.01);吸氧时间和吸氧浓度经非参数两独立样本检验,差异有统计学意义(均P<0.01);退行组的κ_(出生体重/出生孕周)=48.32±11.19;治疗组的κ_(出生体重/出生孕周)=43.94±8.38,经独立样本t检验,二组斜率的差异有统计学意义(t=3.42,P=0.001)。结论同一出生孕周,治疗组的出生体重较退行组更轻,更低的成熟度可能是ROP治疗组的先天因素;吸氧浓度和吸氧时间是促进ROP进展的因素。

Objective Aim To explore the influence factors between the regress team and the therapy team of the ROP.Methods 4360 preterm babies from 1st Jan,2014 to 30nd Dce 2017 were examined.The birth weight,gestational weeks,the time to diagnosis ROP,the oxgen time and the concentration of the oxgen were analysed.The relationship between the birth weight and the gestational weeks were investigated,moreover,the two groups's slope(the birth weight to the gestational weeks)were compared.Results In 414 cases of ROP,the regress team had 326 cases and the therepy team had 88 cases.There were distiguished differences in the birth weight,gestational weeks and the diagosis time between the two groups(P<0.01),furthermore,in the oxgen time and the concentration of the oxgen,also great differences(P<0.01).The difference in slope of birth weight/gesitional age weeks between the two teams was statistically significant(t=3.42,P=0.001).Conclusions At the same gestational weeks,the birth weight in the therpy team was lower than the regress team.The immature was more severe in the therpy team.It may be the origin reason for the therapic ROP.The oxgen time and the concentration of the oxgen may prompt the ROP.