国内女性HPV感染及预防性疫苗接种的研究进展

Research Progress on HPV Infection and Preventive Vaccination among Women in China

目前,人乳头瘤病毒(HPV)感染在全球范围内仍然是一种常见的性传播疾病,对女性健康带来了重大威胁。宫颈癌是女性常见的恶性肿瘤之一,其主要致病原因是高危型别的HPV的持续感染。近年来,随着人们对宫颈癌研究的深入,国内对女性HPV感染情况的研究日趋重视。同时,HPV疫苗作为一种预防HPV感染的有效手段也引起了广泛关注。本文对近年来高危型HPV感染在宫颈癌中作用机制的研究进展、国内女性感染情况,以及HPV预防性疫苗接种情况、存在的问题和未来方向作一综述。

At present,human papilloma virus(HPV)infection remains a common sexually transmitted disease worldwide,posing a significant threat to women’s health.Cervical cancer is one of the common malignant tumors in women,and its main cause is the persistent infection of high-risk HPV.In recent years,with the deepening of research on cervical cancer,research on HPV infection in women in China has become increasingly important.At the same time,the HPV vaccine has also attracted widespread attention as an effective means of preventing HPV infection.This article provides a review of the research progress on the mechanism of high-risk HPV infection in cervical cancer in recent years,the status of female infections in China,as well as the vaccination status,existing problems,and future directions of HPV preventive vaccines.