阿芬太尼在无痛胃肠镜检查麻醉中的应用效果

Effects of Alfentanil Application in Anesthesia for Painless Gastroenteroscopy Examination

目的分析阿芬太尼在无痛胃肠镜检查麻醉中的应用效果。方法选取2022年1月—2023年8月在宁县人民医院接受无痛胃肠镜检查的270例患者为研究对象,采用随机数表法分为对照组(采用常规麻醉)和观察组(采用阿芬太尼麻醉),各135例。对比两组患者苏醒时间、离室时间、丙泊酚用量、术中丙泊酚追加次数,麻醉时血压、心率、呼吸频率、经皮动脉血氧饱和度及不良反应发生率。结果观察组苏醒、离室时间短于对照组,丙泊酚用量和术中丙泊酚追加次数均少于对照组,差异有统计学意义(P均<0.05)。麻醉前,两组舒张压、心率、呼吸频率和经皮动脉血氧饱和度对比,差异无统计学意义(P均>0.05);观察组操作开始时和退镜时的呼吸频率高于对照组,退镜时的收缩压高于对照组,差异有统计学意义(P均<0.05)。观察组的不良反应发生率(0.74%)低于对照组(1.48%),但差异无统计学意义(χ^(2)=0.337,P>0.05)。结论阿芬太尼应用于无痛胃肠镜检查麻醉中效果较好。相较于常规麻醉,阿芬太尼能够缩短患者的苏醒时间和离室时间,减少丙泊酚用量和术中丙泊酚的追加次数,患者术中生命体征更加平稳,手术安全性更高。

Objective To analyze the application effect of alfentanil in anesthesia for painless gastroenteroscopy examination.Methods A total of 270 patients received painless gastroenteroscopy in Ningxian People′s Hospital from January 2022 to August 2023 were selected as the study objects,and they were divided into the control group(using conventional anesthesia)and the observation group(using alfentanil anesthesia)using the random number table method with 135 cases in each group.The awakening time,time to leave the room,propofol dosage,number of intraoperative propofol additions,blood pressure,heart rate,respiratory rate,transcutaneous arterial oxygen saturation values and the incidence of adverse reactions were compared between the two groups.Results The observation group had shorter awakening time and time to leave the room,less propofol dosage and number of intraoperative propofol additions than the control group,and the differences were statistically significant(all P<0.05).Before anesthesia,there was no statistically significant difference in diastolic blood pressure,heart rate,respiratory rate,and percutaneous arterial oxygen saturation between the two groups(all P>0.05).The observation group had a higher respiratory rate at the beginning of the operation and at the time of withdrawal than the control group and systolic blood pressure was higher at the time of withdrawal than that in the control group,and the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the observation group(0.74%)was lower than that in the control group(1.48%),but the difference was not statistically significant(χ^(2)=0.337,P>0.05).Conclusion Afentanil is effective in painless gastroenteroscopy.Compared with conventional anesthesia,alfentanil can shorten the awakening time and departure time,reduce the amount of propofol and the number of additional intraoperative propofol,and provide patients with more stable intraoperative vital signs and higher surgical safety.