577 nm阈值下微脉冲激光在眼底疾病中的应用进展

Monographic Research·Recent Advances in Ophthalmology Technology Progress in the application of micropulse laser under 577 nm threshold in retinal diseases

近年来,阈值下微脉冲激光(SML)作为一种新的视网膜激光治疗技术逐渐引起临床医生的关注。通过重复的微脉冲既可以在"ON时间"有效激活视网膜色素上皮(RPE)细胞,同时又可在"OFF时间"及时散热,避免局部温度过高造成组织损伤。与传统阈值激光(CTL)相比,SML在发挥治疗效果的同时减少了因激光热损伤引起的相关并发症。同时,与抗血管内皮生长因子(VEGF)玻璃体腔注射相比,SML具有成本低、非侵入性等优势。因此,SML治疗正成为治疗多种视网膜脉络膜疾病的方式之一。577 nm SML是其常见的一种类型,理论上此波长的激光在黄斑区内疾病的治疗中具有更高的安全性,本综述旨在总结577 nm SML在常见眼底疾病中的应用进展。

In recent years,Subthreshold Micropulse Laser(SML),as a new retinal laser treatment technology has gradually attracted the attention of clinical doctors.Repeated micro pulses can effectively activate retinal pigment epithelial(RPE)cells during the ON time,while also allowing for timely heat dissipation during the OFF time,avoiding tissue damage caused by excessive local temperature.Compared with traditional threshold laser(CTL),SML not only achieves therapeutic effects but also reduces related complications caused by laser thermal injury.Meanwhile,compared with intravitreal injection of anti vascular endothelial growth factor(VEGF),SML has advantages such as low cost and non invasiveness.Therefore,SML treatment is becoming one of the ways to treat various retinal and choroidal diseases.577 nm SML is a common type of SML,and theoretically,this wavelength of laser has higher safety in the treatment of macular diseases.This review aims to summarize the application progress of 577 nm SML in common retinal diseases.