甲状腺结节患者2型糖尿病患病率和影响因素分析

Analysis of prevalence and influencing factors of type 2 diabetes mellitus in patients with thyroid nodules

目的分析甲状腺结节患者2型糖尿病(type 2 diabetes mellitus,T2DM)的患病率和影响因素。方法回顾性分析2018年1月至2023年8月在杭州市富阳区鹿山街道社区卫生服务中心接受超声检查的甲状腺结节成年患者332例的临床资料,根据有无T2DM将其分为T2DM组(80例)和无T2DM组(252例)。采用多因素Logistic回归分析甲状腺结节患者中T2DM的影响因素。结果两组患者的年龄、25-羟维生素D、游离三碘甲状腺原氨酸、低密度脂蛋白、高密度脂蛋白、三酰甘油、高血压和支气管哮喘比较差异均有统计学意义(P<0.05)。年龄(OR=1.047,95%CI:1.012~1.062)、游离三碘甲状腺原氨酸水平(OR=1.665,95%CI:0.412~1.980)、低密度脂蛋白(OR=1.743,95%CI:0.456~1.907)、高密度脂蛋白(OR=1.664,95%CI:0.465~1.919)、高血压(OR=1.384,95%CI:0.203~1.689)是甲状腺结节成年患者诊断T2DM的影响因素(P<0.05)。结论甲状腺结节患者T2DM患病率较高。年龄、游离三碘甲状腺原氨酸、低密度脂蛋白、高密度脂蛋白和高血压与T2DM和甲状腺结节相关。

Objective To analyze prevalence and influencing factors of type 2 diabetes mellitus(T2DM)in patients with thyroid nodules.Methods Clinical data of 332 adult patients with thyroid nodules underwent ultrasound examination at Community Health Service Center of Lushan Street in Fuyang District,Hangzhou City from January 2018 to August 2023 were retrospectively analyzed.According to presence or absence of T2DM,they were divided into T2DM group(80 cases)and non-T2DM group(252 cases).Influencing factors of T2DM in patients with thyroid nodules were analyzed by using multivariate Logistic regression.Results There were significant differences in age,25-hydroxyvitamin D,free triiodothyronine,low-density lipoprotein,high-density lipoprotein,triglyceride,hypertension and bronchial asthma between two groups(P<0.05).Age(OR=1.047,95%CI:1.012-1.062),free triiodothyronine(OR=1.665,95%CI:0.412-1.980),low-density lipoprotein(OR=1.743,95%CI:0.456-1.907),high-density lipoprotein(OR=1.664,95%CI:0.465-1.919)and hypertension(OR=1.384,95%CI:0.203-1.689)were influence factors for diagnosis of T2DM in adult patients with thyroid nodules(P<0.05).Conclusion Prevalence of T2DM was higher in patients with thyroid nodules.Age,free triiodothyronine,low density lipoprotein,high density lipoprotein and hypertension were associated with T2DM and thyroid nodules.