重组人表皮生长因子对剖宫产腹部切口愈合的疗效

Effect of recombinant human epidermal growth factor on healing of abdominal incision in cesarean section

目的探究重组人表皮生长因子在剖宫产腹部切口愈合中的应用价值。方法将行剖宫产的68例产妇根据随机数字表法分为对照组(34例)与实验组(34例)。对照组实施常规感染治疗,实验组在对照组基础上予以重组人表皮生长因子治疗。对比两组产妇切口愈合情况、切口愈合时间、切口肉芽肿形成时间、切口美观情况、术后并发症发生情况。结果实验组产妇切口愈合情况优于对照组(P<0.05)。实验组产妇切口愈合时间(9.56±1.99)d与切口肉芽肿形成时间(13.35±2.12)d短于对照组的(12.26±2.12)、(16.65±2.65)d(P<0.05)。实验组产妇随访后温哥华瘢痕评价量表(VSS)评分(3.24±1.02)分低于对照组的(5.53±1.26)分(P<0.05)。和对照组(17.65%)相比,实验组产妇并发症发生率(2.94%)较低(P<0.05)。结论将重组人表皮生长因子应用在剖宫产产妇中可加速其腹部切口愈合,保证美观性,值得在临床上推广使用。

Objective To explore the practical value of recombinant human epidermal growth factor on healing of abdominal incision in cesarean section.Methods 68 cases of women who underwent cesarean section were divided into a control group(34 cases)and an experimental group(34 cases)according to the method of randomized numerical table.The control group was treated with conventional infection therapy,and the experimental group was treated with recombinant human epidermal growth factor on the basis of the control group.Both groups were compared in terms of incision healing,incision healing time,incision granuloma formation time,incision aesthetics,and postoperative complications.Results The incision healing in the experimental group was better than that in the control group(P<0.05).The experimental group had incision healing time of(9.56±1.99)d and incision granuloma formation time of(13.35±2.12)d,which were shorter than(12.26±2.12)and(16.65±2.65)d in the control group(P<0.05).After follow-up,the Vancouver Scar Scale(VSS)score of the experimental group was(3.24±1.02)points,which was lower than(5.53±1.26)points of the control group(P<0.05).Compared with the control group(17.65%),the complication rate of the experimental group(2.94%)was lower(P<0.05).Conclusion The application of recombinant human epidermal growth factor in cesarean section can accelerate the healing of abdominal incision,ensure the beauty,and is worthy of clinical application.