从筋骨失衡力学源性分析探讨骨质疏松症的防治策略

Exploring Prevention and Treatment Strategies of Osteoporosis from Analysis of Mechanical Origins of Muscle Bone Imbalance

骨质疏松症(osteoporosis,OP)的诊断率逐年上升,其高发病风险、发病率以及并发脆性骨折,致残、致死率增加给家庭、社会带来极大的危害和负担,也成为世界范围内所面临的老年性、慢性疾病防治的热点和重点问题。从生物力学角度分析其发病过程,明确力学退变性筋骨病原因与其力学平衡和稳定有关的脊柱关节静力系统、肌肉、筋膜、韧带、关节囊等动力系统之间的相互作用,其发生与持续静态负荷和动态负荷、额外负荷、增龄性因素均相关。OP筋-骨系统力学生物学特性失衡,这与现代医学所讲的力学源性平衡因素改变如出一辙。通过对人体力学平衡特点和骨质疏松症患者筋骨失衡的力学源性分析,揭示筋骨系统力学失衡的功能性与结构性代偿临床病理变化分型,针对骨质疏松症患者筋骨力学失衡不同病理分型,为临床防治策略的建立和制定提供参考依据。

The diagnosis rate of osteoporosis(OP)is increasing year by year,and its high risk,incidence and complicated brittle fracture,as well as the increase of disability and mortality,bring great harm and burden to families and society,and become a hot and key issue in the prevention and treatment of senile and chronic diseases around the world.The onset process from the perspective of biomechanics analysis,the interact of mechanics degenerative bones and muscles disease reasons related to its mechanical balance and stability of spinal joint static system,muscle and fascia,ligaments and joint capsule can be clear.Its occurrence is related to sustained static and dynamic loads,additional loads and age-related factors.The mechanical and biological characteristics of the OP tendon-bone system are imbalanced,which is similar to the changes in the mechanical balance factors discussed in modern medicine.By analyzing the mechanical balance characteristics of the human body and the mechanical origin of skeletal and fascial imbalances in patients with OP,this study reveals the functional and structural compensatory clinical pathological changes of skeletal and fascial system mechanical imbalances.Different pathological classifications of skeletal and fascial mechanical imbalances in patients with OP are targeted,providing reference basis for the establishment and formulation of clinical prevention and treatment strategies.