oXiris滤器和M150滤器治疗急性肾损伤对患者肾功能、血清炎症因子及预后影响

The Effects of oXiris Filter and M150 Filter in the Treatment of Acute Kidney Injury on Renal Function,Serum Inflammatory Factors,and Prognosis

目的:研究oXiris滤器和M150滤器治疗急性肾损伤对患者肾功能、血清炎症因子及预后的影响。方法:选取74例急性肾损伤患者为研究对象,基于连续性肾脏替代治疗所用滤器类型不同将其分为两组,研究组和对照组分别采用oXiris滤器和M150滤器,观察两组治疗效果、治疗前后肾功能指标和血清炎症因子、预后和生存情况。结果:研究组各疗效指标以及预后均优于对照组(P<0.05)。治疗前两组各项肾功能指标和血清炎症因子差异均无统计学意义(P>0.05),治疗后两组各项肾功能指标和血清炎症因子均较治疗前明显改善,但组间差异均无统计学意义(P>0.05)。两组存活率差异无统计学意义(P>0.05)。结论:oXiris滤器和M150滤器均能有效改善急性肾损伤患者肾功能和血清炎症因子水平,但是在临床疗效和预后方面oXiris滤器更具优势。

Objective:To study the effects of oXiris filter and M150 filter on renal function,serum inflammatory factors,and prognosis in patients with acute kidney injury.Methods:74 patients were selected and divided into two groups based on the types of filters.The study group and the control group were treated with oXiris filters and M150 filters respectively.Observe the therapeutic effects,renal function indicators,serum inflammatory factors,prognosis and survival.Results:The therapeutic indicators and prognosis of the study group were better than those of the control group(P<0.05).There was no statistically significant difference in various renal function indicators and serum inflammatory factors between the two groups before treatment(P>0.05);After treatment,both groups showed significant improvements in various renal function indicators and serum inflammatory factors compared to before treatment,but there was no statistically significant difference between the groups(P>0.05).There was no statistically significant difference in survival rates between the two groups(P>0.05).Conclusion:Both oXiris filters and M150 filters can effectively improve renal function and serum inflammatory factor levels,but oXiris filters have advantages in clinical efficacy and prognosis.