宫腔镜术后辅助地屈孕酮治疗对子宫内膜息肉患者临床疗效及预后的影响

Effects of Adjuvant Dydrogesterone Therapy on Clinical Efficacy and Prognosis of Patients with Endometrial Polyps after Hysteroscopy

目的:探讨宫腔镜术后辅助地屈孕酮治疗,对子宫内膜息肉(EP)患者的临床疗效及预后.方法:选取2019年1月至2022年12月本院收治的82例EP患者作为研究对象.根据治疗方式不同将其分为观察组[n=43,采取宫腔镜下息肉摘除术(TCRP)后联合地屈孕酮片治疗]和对照组(n=39,仅采取TCRP治疗).对比两组治疗效果、子宫内膜变化情况及EP复发率.结果:观察组治疗总有效率显著高于对照组,差异有统计学意义(P<0.05).治疗后,两组患者子宫内膜厚度及月经量,均较其治疗前显著降低,且观察组显著低于对照组,差异均有统计学意义(P<0.05).TCRP后随访至3个月及6个月时,观察组复发率均显著低于对照组,差异均有统计学意义(P<0.05).结论:宫腔镜术后辅助地屈孕酮治疗EP的临床疗效显著,能有效改善患者临床症状,降低复发率,具有良好的临床参考价值.

Objective:To explore the effects of adjuvant dydrogesterone therapy on the clinical efficacy and prognosis of patients with endometrial polyps(EP)after hysteroscopy.Methods:Eighty-two EP patients admitted to our hospital from January 2019 to December 2022 were selected as the research subjects.They were divided into observation group[n=43,tanscervical resection(TCRP)+dydrogesterone tablet treatment]and control group(n=39,TCRP treatment).Compare the treatment effects,endometrial changes,and recurrence rates between two groups.Results:The total effective rate of clinical efficacy in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).After treatment,endometrial thickness and menstrual flow decreased in the two groups,and the observation group were lower than the control group,the differences were statistically significant(P<0.05).3 months and 6 months after TCRP,the postoperative recurrence rates in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion:The clinical efficacy of dydrogesterone in the treatment of EP after hysteroscopy is significant,which can effectively improve the clinical symptoms of patients,and reduce the recurrence rate,and has a good reference value.