柔性可穿戴传感器用于心血管疾病监测的研究进展

Research Progress of Flexible Wearable Sensors for Cardiovascular Disease Monitoring

心血管疾病在我国的发病率和死亡率均处首位,并且呈现持续上升和年轻化的趋势,已成为重大的公共卫生问题。近年来,柔性电子技术在医疗健康领域得到广泛应用,为多种疾病的早期诊断和精细管理提供了新的途径。尤其是对于具有急起病、常复发、易隐匿等特点的心血管疾病,柔性电子技术能够显著提高可穿戴传感器的佩戴舒适性和监测准确性。结合柔性电子和可穿戴传感器的发展趋势,在介绍可穿戴心血管传感技术分类和原理的基础上,综述其在监测心率、血压、血流、血氧饱和度等心血管疾病重要指标的研究进展,探讨柔性可穿戴传感器在心血管诊疗领域所面临的挑战和需要解决的问题,并展望了相应的发展方向。

As cardiovascular diseases ranking first in terms of morbidity and mortality in China and showing a tendency of continuous increase and rejuvenation,they have become a major public health concern.Recently,flexible electronic technology has been widely used in the healthcare industry,offering new approaches for timely detection and precise management of various diseases.Notably,the flexible electronic technology can greatly improve the wearing comfort and monitoring accuracy of wearable sensors for cardiovascular diseases,which are characterized by acute onset,frequent recurrence and insidiousness.In this review,classifications and principles of wearable sensor technologies are briefly introduced in combination with the development trend of flexible electronics and wearable sensors.Recent advances in flexible wearable sensors are discussed,with a primary focus on monitoring important parameters related to cardiovascular disease,including heart rate,blood pressure,blood flow and oxygen saturation.Finally,this article discusses the challenges and issues that need to be addressed for flexible wearable sensors in the field of cardiovascular diagnosis and treatment,and suggests the corresponding development directions.