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环泊酚及其在临床中的应用

Introduction of cyclopofol and its clinical application
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摘要 环泊酚是新型静脉麻醉药物,其药物特点与丙泊酚类似。目前已有多项临床试验证实,环泊酚具有起效快、恢复快等特点,可用于全身麻醉诱导、无痛胃肠镜检查、纤维支气管镜检查等,在重症监护室和老年患者中应用有一定的优势。环泊酚的安全性较高,且引起的注射痛发生率明显低于丙泊酚。随着环泊酚在临床的逐步应用,其应用范围、作用机制及优势等值得进一步研究。 Cyclopofol is a new type of intravenous anesthesia drug,with drug characteristics similar to propofol.At present,multiple clinical trials have confirmed that cyclopofol has the characteristics of fast onset and recovery,and can be used for general anesthesia induction,painless gastroscopy,fiberoptic bronchoscopy,etc.It has certain advantages in the application of intensive care units and elderly patients.The safety of cyclopofol is relatively high,and the incidence of injection pain caused by cyclopofol is significantly lower than that of propofol.With the gradual application of cyclopofol in clinical practice,its scope of application,mechanism of action,and advantages are worthy of further research.
作者 管钊铭 于淼 梁涛 李斯羽 韩丹 季中华 王颖林 GUAN Zhao-ming;YU Miao;LIANG Tao;LI Si-yu;HAN Dan;JI Zhong-hua;WANG Ying-lin(Shanghai East Hospital/East Hospital Affiliated to Tongji University,SHANGHAI 200120,China)
出处 《中国新药与临床杂志》 CAS CSCD 北大核心 2024年第4期253-256,共4页 Chinese Journal of New Drugs and Clinical Remedies
关键词 环泊酚 丙泊酚 麻醉 临床应用 cyclopofol propofol anesthesia clinical application
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