三棱研究热点的CiteSpace科学文献可视化分析

CiteSpace scientific literature visual analysis of research hotspots of Sparganii Rhizoma

目的基于知识图谱方法对三棱近10年研究热点及趋势进行可视化分析,为未来该领域的研究提供参考。方法选取2012年1月1日至2022年1月1日中国知网(CNKI)中有关三棱的研究,运用CiteSpace软件对纳入研究的样本文献进行分析,并绘制年发文量、作者合作网络、机构合作网络、关键词共现、关键词聚类、关键词突现图谱。结果最终纳入592篇文献,年发文量较为平稳;形成以时海燕、侯睿捷、梁侨丽为代表的团队,各机构间合作较少。频次较高的关键词包括数据挖掘、用药规律、三棱等,共形成10个聚类;研究热点主要集中于妇科及肿瘤等疾病的用药规律、临床研究和相关作用机制;关键词突现分析共得到43个突现词,以数据发掘、临床研究及治疗肿瘤与妇科疾病的研究较多,实验室研究对有效成分的提取及其活性成分作用机制较为重视。结论近年来,三棱的研究热点主要集中在妇科和肿瘤疾病的临床用药总结以及抗纤维化机制的初步探究,未来或将深入探求其抗肿瘤作用靶点,并逐渐延伸至对器官纤维化等难治性疾病的治疗靶点研究及临床用药规律总结。

AIM To visually analyze the research hotspots and trends of Spargani Rhizoma in the past 10 years based on the knowledge mapping method to provide references for future research in this field.METHODS The research on Spargani Rhizoma from January 1st,2012 to January 1st,2022 were selected from CNKI,and the sample literature included in the study was analyzed using CiteSpace software,and the annual publication volume,author collaboration network,institutional collaboration network,keyword co-occurrences,keyword clustering,and keyword emergent mapping were drawn.RESULTS A total of 592 papers were included,and the annual publication volume was relatively stable.The team represented by SHI HY,HOU RJ and LIANG QL was formed,and there was less cooperation among institutions.The keywords with higher frequency include data mining,medication law,Sparganii Rhizoma,etc.,forming 10 clusters.The research hotspots mainly focus on gynecological diseases and tumors,clinical research,mechanism of action,etc.The keyword emergence analysis obtained a total of 43 emergent words,with more research on data mining,clinical research,and treatment of tumors and gynecological diseases,and the laboratory research pays more attention to the extraction of the active ingredient and its active ingredients and the mechanism of action.Laboratory studies paid more attention to the extraction of active ingredients and their active components.CONCLUSION In recent years,the research hotspots of Spargani Rhizoma mainly focuses on the clinical medication for gynecological and oncological diseases,and gradually extends to the treatment of refractory diseases such as organ fibrosis.In the future,the research direction of Spargani Rhizoma will tend to be more towards the research of the target mechanism and the summary of the law of medication.