应用灸法治疗盆腔炎性疾病后遗症的现代研究进展

Modern Research Progress of Moxibustion Treating Sequelae of Pelvic Inflammatory Diseases

盆腔炎性疾病后遗症(SPID)是妇科的常见病、多发病,临床疗效不佳且迁延难愈。现代医学认为SPID患者多由于机体免疫力下降,内源性病原体过度繁殖,加之外源性病原体侵袭,受损细胞组织不断释放炎症因子,使盆腔组织持续处于低度炎性状态,导致组织破坏粘连、增生等病理改变。艾灸疗法是中医治疗SPID疾病的常用方法,相关研究表明灸法可以通过多靶点、多环节调控炎症水平,促进盆腔组织的炎症吸收消散,重建盆腔组织内环境平衡,还能有效调节疾病引起的抑郁焦虑等负性情绪,增强患者依从性。目前灸法治疗SPID已经取得了一定的成果,且能够有效改善SPID患者临床症状和体征。故该文从抑菌、调控炎性反应、修复免疫损伤、改善血液循环及缓解负性情绪五个方面对近年灸法治疗SPID的研究进行归纳总结,发现艾灸对SPID有着较好的临床疗效,并进一步明确艾灸干预SPID的效应机制,在此基础上,探讨目前存在的不足,以期为今后的相关研究提供参考。

The sequelae of pelvic inflammatory disease(SPID)is a common and frequently-occurring disease in gynecolo-gy,with poor clinical effect and difficult to cure.Modern medicine believes that SPID patients are mainly due to the decline of body immunity,the excessive reproduction of endogenous pathogens,and the invasion of exogenous pathogens,and the damaged cells and tissues continue to release inflammatory factors,which keeps the pelvic tissues in a state of low inflammation,resulting in pathological changes such as tissue destruction and adhesion,proliferation and so on.Moxibustion therapy is a common method used in the treatment of SPID diseases in traditional Chinese medicine.Relevant studies have shown that moxibustion can regu-late the level of inflammation through multiple targets and multiple links,promote the absorption and dissipation of inflammation in the pelvic tissue,restore the environmental balance in the pelvic tissue,effectively regulate the negative emotions caused by the disease,such as depression and anxiety,and enhance patients'compliance.At present,moxibustion has achieved certain results in the treatment of SPID,and can effectively improve the clinical symptoms and signs of patients with SPID.Therefore,this paper summarized the recent studies on moxibustion treatment of SPID from five aspects,including bacteriostasis,regulation of inflamma-tion,repair of immune damage,improvement of blood circulation and relief of negative emotions.It is found that moxibustion has a good clinical effect on SPID,and further defines the effect mechanism of moxibustion intervention on SPID.On this basis,the current shortcomings were discussed in order to provide reference for future related research.