消癖散结汤联合情志疗法治疗乳腺增生的临床疗效及安全性分析

Analysis of clinical efficacy and safety of Xiaopi Sanjie Decoction combined with emotional therapy in the treatment of breast hyperplasia

目的 分析消癖散结汤联合情志疗法治疗乳腺增生的临床疗效及安全性。方法 140例乳腺增生患者,根据住院单双号分为对照组和观察组,每组70例。两组患者均给予西药常规治疗,在此基础上,对照组患者给予情志疗法治疗,观察组在对照组基础上增加消癖散结汤治疗。比较两组乳腺疼痛消失时间、乳腺肿块消失时间、治疗效果及治疗前后生活质量评分;观察不良反应发生情况。结果观察组乳腺疼痛消失时间(6.21±1.21)d、乳腺肿块消失时间(8.19±2.12)d短于对照组的(9.56±2.91)、(11.25±3.21)d(P<0.05)。治疗后,两组物质生活、躯体功能、心理功能、社会功能评分均高于本组治疗前,且观察组物质生活评分(92.12±6.94)分、躯体功能评分(93.21±5.23)分、心理功能评分(93.12±4.94)分、社会功能评分(93.21±5.56)分显著高于对照组的(82.45±6.12)、(83.21±4.12)、(83.45±4.34)、(82.55±5.12)分(P<0.05)。观察组总有效率94.29%高于对照组的74.29%(P<0.05)。两组治疗过程未见不良反应。结论 情志疗法联合消癖散结汤对乳腺增生的治疗效果确切,可提高生活质量,安全性高。

Objective To analyze the clinical efficacy and safety of Xiaopi Sanjie Decoction combined with emotional therapy in the treatment of breast hyperplasia.Methods A total of 140 patients with breast hyperplasia were divided into a control group and an observation group by odd-even number of hospitalization,with 70 patients in each group.Both groups were given conventional Western medicine treatment.On this basis,patients in the control group were treated with emotional therapy,and patients in the observation group were treated with Xiaopi Sanjie Decoction on the basis of the control group.The time for the disappearance of breast pain,the time for the disappearance of breast mass,therapeutic effect,the quality of life score before and after treatment were compared between the two groups,and the occurrence of adverse reactions was observed.Results The time for the disappearance of breast pain and mass in the observation group were(6.21±1.21)and(8.19±2.12)d,which were shorter than(9.56±2.91)and(11.25±3.21)d in the control group(P<0.05).After treatment,the scores of material life,physical function,psychological function and social function in both groups were higher than those before treatment;the observation group had physical life score of(92.12±6.94),physical function score of(93.21±5.23),psychological function score of(93.12±4.94)and social function score of(93.21±5.56)points,which were significantly higher than(82.45±6.12),(83.21±4.12)and(83.45±4.34)and(82.55±5.12)points in the control group(P<0.05).The total effective rate of the observation group was 94.29%,which was higher than 74.29%of the control group(P<0.05).No adverse reactions were observed in the two groups.Conclusion Emotional therapy combined with Xiaopi Sanjie Decoction is effective in the treatment of breast hyperplasia,which can improve the quality of life and has high safety.