临床药师干预呼吸内科喹诺酮类抗菌药物使用的效果评价

Evaluation of the effect of clinical pharmacist intervention in the use of quinolones in respiratory medicine

目的 评价临床药师干预呼吸内科喹诺酮类抗菌药物使用的效果,规范喹诺酮类抗菌药物的使用,促进该类药物在临床的合理使用。方法 选取临床药师审核并干预的呼吸内科不合理使用喹诺酮类抗菌药物的患者病历42份。对喹诺酮类抗菌药物不合理的使用情况进行分析和评价,总结出不合理使用喹诺酮类抗菌药物的常见问题,并提出审核建议及改进措施。结果 呼吸内科不合理使用喹诺酮类抗菌药物的原因主要为无指征联合用药和用药时程过长,构成比分别为42.86%和26.19%,其次为用药禁忌、药物相互作用、用药不适宜和药物剂量过大,构成比分别为9.52%、9.52%、7.14%和4.76%。临床药师给出医嘱审核建议, 36份医嘱进行重整,采纳率为85.71%。结论 临床药师在干预呼吸内科喹诺酮类抗菌药物使用中发挥了重要作用,提高了临床抗菌药物合理的使用,保证了患者的用药安全。

Objective To evaluate the effect of clinical pharmacist intervention in the use of quinolones in respiratory medicine,so as to standardize the use of quinolones and promote the rational use of these drugs in clinic.Methods 42 medical records of patients with unreasonable use of quinolones in respiratory department reviewed and intervened by clinical pharmacists were selected.The irrational use of quinolones was analyzed and evaluated,the common problems of irrational use of quinolones were summarized,and the review suggestions and improvement measures were put forward.Results The main reasons for irrational use of quinolones in respiratory medicine were unindicated combination and excessive duration of medication,accounting for 42.86%and 26.19%,respectively,followed by contraindications to medication,drug interactions,inappropriate medication,and excessive medication dosage,accounting for 9.52%,9.52%,7.14%,and 4.76%,respectively.Clinical pharmacists gave recommendations for review of medical prescriptions and 36 prescriptions were reorganized with an adoption rate of 85.71%.Conclusion Clinical pharmacists played an important role in intervening the use of antibacterial drugs,which improved the rational use of clinical antibacterial drugs and ensured the safety of patients.