眼球生物学参数与儿童近视的相关性分析及预防干预措施

Correlation Analysis and Preventive Intervention Measures between Biological Parameters of the Eyeball and Myopia in Children

【目的】探讨眼球生物学参数与儿童近视的相关性及预防干预措施。【方法】选取2019年1月至2021年12月本院眼科门诊就诊的500例儿童,根据是否近视分为近视组与非近视组,比较两组眼球生物学参数[眼轴长度(AL)、眼轴长度与角膜曲率比(AL/CR)、晶状体厚度(LT)、白到白的距离(WTW)、角膜厚度(CT)、玻璃体腔长度(VCL)及眼内压(IOP)]、性别、年龄及行为方式(桌椅高度、使用电子产品时间、户外运动时间及用眼时间);采用Logistic回归分析儿童近视的影响因素;采用Pearson分析儿童近视与眼球生物学参数的相关性。【结果】两组AL、AL/CR、LT、CT、VCL、年龄及行为方式比较,差异均有统计学意义(均P<0.05)。Logistic回归分析结果显示:AL、AL/CR、LT、CT、VCL、年龄、行为方式均是儿童近视的影响因素(P<0.05)。Pearson相关性分析显示:AL、AL/CR、VCL与儿童近视呈正相关(r=0.472、0.369、0.449,均P<0.05),LT、CT与儿童近视呈负相关(r=-0.210、-0.170,P<0.05)。【结论】眼球生物学参数、年龄、行为方式与儿童近视密切相关。

【Objective】To explore the correlation between biological parameters of the eyeball and myopia in children and preventive interventions.【Methods】A total of 500 children diagnosed and treated in the ophthalmology outpatient department of our hospital from January 2019 to December 2021 were selected.They were divided into myopia group and non myopia group based on whether they were nearsighted.The biological parameters of the eyeballs in the two groups were compared in terms of Axial length(AL),axial length to corneal curvature ratio(AL/CR),lens thickness(LT),white to white distance(WTW),corneal thickness(CT),vitreous cavity length(VCL),and intraocular pressure(IOP),gender,age,and behavioral patterns(table and chair height,time spent using electronic devices,outdoor exercise time,and eye use time);Logistic regression was used to analyze the influencing factors of myopia in children;Pearson analysis was used to investigate the correlation between myopia in children and ocular biological parameters.【Results】The AL,AL/CR,LT,CT,VCL,Age and behavior patterns of two groups of were compared,and the differences were statistically significant(all P<0.05).The results of logistic regression analysis showed that:AL,AL/CR,LT,CT,VCL,Age and behavioral patterns were both influencing factors for myopia in children.Pearson correlation analysis shows that AL,AL/CR,VCL were positively correlated with myopia in children(r=0.472,0.369,0.449,all P<0.05);LT,CT were negatively correlated with myopia in children(r=-0.210,-0.170,P<0.05).【Conclusion】Eye biological parameters,age,and behavioral habits are closely related to myopia in children.