非幽门螺杆菌螺杆菌研究进展

Research progress in non-Helicobacter pylori Helicobacter species

非幽门螺杆菌螺杆菌(non-Helicobacter pylori Helicobacter species,NHPHs)是除幽门螺杆菌(Helicobacter pylori,H.pylori)以外的螺杆菌。NHPHs具有潜在人兽共患风险,可能会引起人和犬猫的胃肠道疾病。NHPHs感染人和动物后通常定植于胃肠道,根据其定植位置的不同可以将其分为胃NHPHs和肠肝NHPHs。犬猫感染NHPHs后可能会通过粪便、唾液、胃液将病原传播给人,从而引发人的胃炎、胃溃疡、肠炎等。本文从病原学、流行病学、临床表现和公共卫生风险方面介绍了人和犬猫感染非幽门螺杆菌螺杆菌的研究进展,旨在守护人类和动物的健康。

Non-Helicobacter pylori Helicobacter species(NHPHs)are Helicobacter species other than Helicobacter pylori(H.pylori).They are potential zoonotic pathogens that usually colonize the gastrointestinal tract of humans,dogs and cats,resulting in gastrointestinal diseases.Based on the site of colonization,NHPHs are classified as gastric or enterohepatic.NHPHs infecting dogs and cats may spread to humans through feces,saliva and gastric juices,causing human gastritis,gastric ulcer,and enteritis.This review summarizes recent progress of the etiology,epidemiology,and clinical and public health implications of NHPHs in humans,dogs and cats.