关注尿沉渣评分 助力肾损伤诊断

To pay close attention to urine sediment microscopy again,and to assist with diagnosis of kidney injury

尿液承载着人体代谢丰富的信息,尿液检查有助于急性肾损伤(AKI)和慢性肾脏病(CKD)的诊断分型及疗效观察,尿沉渣具有简便、初筛、定性、定位的特点,为鉴别红细胞来源、协助诊断肾小球疾病、泌尿系感染以及各种原因的肾实质损伤提供了重要依据。随着对早期诊断AKI尿生物标志物研发的不断深入,尿沉渣作为尿生物标志物用于AKI 诊断的临床意义被重新认识。尿沉渣镜检有形成分中基于肾小管上皮细胞(RTEC)和颗粒管型(GC)计数的尿沉渣评分方法,主要有尿沉渣评分(USS)、管型评分指数(CSI)、尿液显微镜检查评分(UMS)和连续尿沉渣显微镜检查(MicrExUrSed),可为AKI早期诊断、病因鉴别、评估分期、判断预后提供实验室信息。

Urine carries rich information of human metabolism,while urine examination facilitates the diagnosis,classification and efficacy observation for acute kidney injury(AKI)and chronic kidney disease(CKD).Urine sediment has characteristics of convenience,screening,qualitation,localization,which provides important basis for distinguishing the source of RBC,assisting in the diagnosis of renal glomerular diseases,urinary infection and various causes of renal parenchymal injury.The urine sediment microscopy based on renal tubular epithelial cell(RTEC)and granular tubular(GC)counts mainly includes urinary sediment score(USS),tubular scoring index(CSI),urine microscopy score(UMS),and continuous urine sediment microscopy score(MicrExUrSed),which can provide laboratory information for early diagnosis,etiological differentiation,staging evaluation,and prognosis assessment of AKI.