青海西宁城市湿地地表水中抗生素的赋存特征和生态风险

Spatio-temporal Variations and Ecological Risks of Antibiotic Occurrence in Urban Wetlands of Xining,Qinghai Province

于2022年3月和7月,采用液相色谱-串联质谱法,测定了青海西宁4处城市湿地地表水中16种典型抗生素的浓度,分析和探讨了抗生素时空分布特征及潜在生态风险。研究结果表明,西宁城市湿地地表水中抗生素在3月和7月分布差异显著,3月共检出16种抗生素,平均浓度范围为0.18~164.15 ng/L,7月共检出6种抗生素,平均浓度范围为0.15~43.22 ng/L,空间分布受人类活动的影响;恩诺沙星和双氟沙星浓度与盐度、电导率和溶解性固体总量的含量都显著正相关,氧氟沙星、诺氟沙星和泰乐霉素浓度与化学需氧量显著正相关,洛美沙星浓度与电导率含量显著正相关,氟罗沙星浓度与总磷含量显著正相关,氧四环素浓度与硝酸盐氮含量显著正相关,抗生素污染受水质指标的影响;3月氧氟沙星、诺氟沙星和环丙沙星的风险商(RQ)值分别为108.04、5.02和4.90,生态风险水平为高风险,7月氧氟沙星的风险商值为26.59,为高风险,其他抗生素为中风险、低风险和无风险。

In March and July 2022,the concentrations of 16 typical antibiotics in the surface water of four urban wetlands in Xining,Qinghai,were tested by liquid chromatography-tandem mass spectrometry,and the spatial and temporal distribution characteristics of the antibiotics as well as the potential ecological risks were further explored and analyzed.It comes out that the distribution of antibiotics in the urban wetland surface water was significantly different between March and July.Precisely,in March,16 antibiotics were detected,with the average concentration ranging from 0.18 to 164.15 ng/L,and in July,6 antibiotics were detected,with the average concentration ranging from 0.15 to 43.22 ng/L.The spatial distribution was affected by human activities.There was a significant positive correlation between norfloxacin concentration and chemical oxygen demand.The fleroxacin concentration was correlated positively with that of phosphorus total content.Ofloxacin concentration was also correlated positively with total phosphorus and nitrogen content.Antibiotic pollution is affected by water quality indicators.The risk quotient values of ofloxacin,norfloxacin,and ciprofloxacin in March were 108.04,5.02 and 4.90,respectively,with possibility of high level of ecological risk,and identically the ofloxacin presents high ecological risk in July,with value of 26.59.Other antibiotics were medium risk,low risk and no risk.