瑞马唑仑麻醉的研究现状:基于文献计量学的分析

Research progress on remazolam anesthesia:bibliometrics-based analysis

目的基于文献计量学分析瑞马唑仑麻醉的研究概况、热点变化和发展趋势。方法检索Web of Science核心合集数据库2010年1月至2023年6月瑞马唑仑的相关研究文献,应用文献计量学方法并借助信息分析软件VOS viewer对瑞马唑仑在麻醉研究中的发表年份分布、文献研究方法、研究人群分布、所属国家/地区分布、作者及机构分布、文献刊载来源分布、研究热点分析以及共被引期刊和文献进行共现和聚类分析,并绘制图谱。结果检索到瑞马唑仑相关文献360篇,且在麻醉相关的研究中发文量逐年上升;研究类型以临床研究为主,研究人群中老年患者多于儿童患者;目前中国是发文量最多的国家,美国文献的被引频次居于前列;瑞马唑仑相关研究发文量≥5篇的作者17位、机构22个;刊文量≥10篇的期刊有8种;研究热点分析显示“咪达唑仑”“丙泊酚”“安全性”“镇静”“麻醉”为研究热点关键词;另外,有35篇文献共被引次数在20次及以上,其中共被引次数排名前10的文献有3篇来自Anesthesia and Analgesia。结论瑞马唑仑在麻醉中作用的关注度逐年升高,目前的研究热点包括瑞马唑仑在胃肠镜检查、手术、全身麻醉以及重症监护治疗病房中的镇静疗效。瑞马唑仑有望成为临床上广泛应用的镇静药物。

Objective To explore the research profile,topical changes,and trends in remimazolam anesthesia through bibliometrics⁃based analysis.Methods Retrieved the core database of Web of Science about remimazolam from January 2010 to June 2023,and analyzed the distribution of year of publication,methodology,population,country/region,authors and institutions,dis⁃tribution of publication sources,research hotspots,and co⁃cited journals and literature in anesthesia research through bibliometrics methods and the information analysis software VOS viewer for co⁃occurrence and clustering,and mapping.Results There were 360 articles related to remazolam,and the number of articles published in anesthesia⁃related research increased year by year.Clinical research is the main focus,and the number of elderly patients exceeds that of pediatric patients in the study population.China is cur⁃rently the country with the largest number of articles,while the United States is at the forefront of the citation frequency.There are 17 authors and 22 institutions with≥5 publications on remazolam⁃related studies.There are 8 journals with 10 or more articles.Accord⁃ing to the analysis of research hotspots,"midazolam","propofol","safety","sedation"and"anesthesia"were the terms of research hot⁃spot.Furthermore,there were 35 articles with 20 or more total citations,with three of the top 10 co⁃citations from the journal Anesthe⁃sia and Analgesia.Conclusions The role of remazolam in anesthesia has drawn increasing attention year by year.The current re⁃search hotspots include the sedative efficacy of remazolam in gastro enteroscopy,surgery,general anesthesia,and intensive care units.Remazolam is expected to become a widely used sedative drug in clinical practice.