中暑患者发生热射病的危险因素探讨

Risk factors of heat stroke in patients with sunstroke

目的探讨中暑患者发生热射病的危险因素,为预防和治疗热射病提供理论依据。方法抽取2018年1月至2023年1月联勤保障部队第九七〇医院收治的热射病和轻中度中暑患者120例进行回顾性研究,其中60例热射病患者作为热射病组,60例轻中度中暑患者作为中暑组。采集患者入院时的病例资料,并予以归纳总结,比较两组患者上述指标差异,以患者是否发生热射病为因变量对患者进行Logistic多因素回归分析。结果热射病组患者年龄、白细胞计数、血红蛋白、天冬氨酸转氨酶、丙氨酸转氨酶、肌酸激酶、凝血酶原时间、凝血酶时间(TT)均高于中暑组(P均<0.05)。Logistic多因素回归分析结果显示,TT是影响中暑患者发生热射病的危险因素(P<0.05)。TT预测中暑患者发生热射病的受试者工作特征曲线下面积为0.67。结论TT为影响中暑患者发生热射病的危险因素,且对于预测中暑患者是否会发生热射病具有重要价值。

Objective To investigate the risk factors of heat stroke in patients with sunstroke,and provide theoretical basis for the prevention and treatment of heat stroke.Methods A retrospective study was conducted on 120 patients with heat stroke or mild to moderate sunstroke admitted to No.970th Hospital of the Joint Logistic Support Force from January 2018 to January 2023.Among them,60 patients with heat stroke were selected as the heat stroke group,and 60 patients with mild to moderate sunstroke were selected as the sunstroke group.Case data at the time of admission were collected and summarized,and the differences in the above indicators between the two groups were compared.Logistic multivariate regression analysis was performed on with the occurrence of heat stroke as dependent variable.Results The age,and levels of white blood cell count,hemoglobin,aspartate transaminase,alanine transaminase,creatine kinase,prothrombin time and thrombin time(TT)in the heat stroke group were all higher than those in the sunstroke group(all P<0.05).Results of multivariate logistic regression analysis showed that TT was a risk factor for development of heat stroke in patients with sunstroke(P<0.05).The area under the receiver operating characteristic curve of TT in predicting heat stroke in patients with sunstroke was 0.67.Conclusions Thrombin time is a risk factor of developing heat stroke in patients with sunstroke,and it has important value in predicting whether they will develop heat stroke.