嗜铬细胞瘤及副神经节瘤不同生化表型的CT征象对比研究

Comparative Study of CT Signs of Different Biochemical Phenotypes in Pheochromocytoma and Paraganglioma

本研究的目的是分析生化阴性嗜铬细胞瘤及副神经节瘤的电子计算机断层扫描征象是否有别于生化阳性PPGLs,同时了解生化阳性PPGLs不同表型的CT征象是否存在差异。对此,我们对西南医科大学附属医院2023年5月-2023年11月30例经手术病理证实的嗜铬细胞瘤及副神经节瘤患者进行了回顾性研究,其中15例为生化阳性PPGLs,15例为生化阴性PPGLs。所有患者均进行了电子计算机断层扫描(CT)检查。我们比较了两组患者的CT征象,包括肿瘤的形态、密度、强化特点以及周围组织的受累情况。结果显示,生化阴性PPGLs在CT上表现为肿瘤形态不规则,密度不均匀,强化不显著,周围组织受累较少。而生化阳性PPGLs在CT上表现为肿瘤形态规则,密度均匀,强化显著,周围组织受累较多。此外,我们还发现生化阳性PPGLs中不同表型(如肾上腺素型、去甲肾上腺素型等)的CT征象也有所不同,这有助于临床医生更准确地判断肿瘤类型。

The purpose of this study is to analyze whether the electronic computed tomography signs of biochemical negative pheochromocy-toma and paraganglioma are different from those of biochemical positive PPGLs,and to understand whether there are differences in CT signs of different phenotypes of biochemical positive PPGLs.We conducted a retrospective study on 30 patients with pathologically confirmed pheochromocytoma and paraganglioma at the Affiliated Hospital of Southwest Medical University from May 2023 to November 2023.Among them,15 were biochemical positive PPGLs and 15 were biochemical negative PPGLs.All patients underwent electronic computed tomogra-phy(CT)examination.We compared the CT features of two groups of patients,including tumor morphology,density,enhancement character-istics,and involvement of surrounding tissues.The results showed that biochemical negative PPGLs exhibited irregular tumor morphology,uneven density,insignificant enhancement,and less involvement of surrounding tissues on CT.Biochemically positive PPGLs on CT show regular tumor morphology,uniform density,significant enhancement,and more involvement of surrounding tissues.In addition,we also found that the CT signs of different phenotypes(such as adrenaline type,norepinephrine type,etc.)in biochemical positive PPGLs are differ-ent,which helps clinical doctors to more accurately determine the type of tumor.