重复经颅磁刺激联合康复训练治疗单侧空间忽略的临床效果

Clinical Efficacy of Repeated Transcranial Magnetic Stimulation Combined with Rehabilitation Training in the Treatment of Unilateral Spatial Neglect

目的:探讨重复经颅磁刺激联合康复训练治疗单侧空间忽略的临床效果。方法:选择2021年6月—2023年6月浙江中医药大学附属金华市中医医院收治的60例单侧空间忽略患者作为研究对象。根据随机数表法均分为对照组和观察组,各30例。对照组应用康复治疗,研究组在康复训练基础上联合重复经颅磁刺激治疗。比较两组忽略症状情况、Fugl-Meyer运动功能量表(FMA)、改良Barthel指数(BI)、简易精神状态检查量表(MMSE)等指标。结果:干预后,两组字体抄写试验、画钟试验、线段划消试验、直线二等分试验、平面图形临摹试验评分均低于干预前,且研究组低于对照组,差异有统计学意义(P<0.05)。干预后,两组FMA评分、MMSE评分、BI评分均高于干预前,且研究组高于对照组,差异有统计学意义(P<0.05)。结论:在康复训练基础上联合重复经颅磁刺激治疗单侧空间忽略可有效改善患者临床症状及认知功能,提升患者独立性和日常生活能力。

Objective:To investigate the clinical effect of repeated transcranial magnetic stimulation combined with rehabilitation training on unilateral spatial neglect.Method:A total of 60 patients with unilateral spatial neglect admitted to Jinhua Traditional Chinese Medicine Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine from June 2021 to June 2023 were selected as the study objects.According to random number table method,they were divided into control group and observation group,with 30 cases in each group.The control group received rehabilitation therapy,and the study group received repeated transcranial magnetic stimulation based on rehabilitation training.The ignore symptoms,Fugl-Meyer motor function scale(FMA),modified Barthel index(BI),and mini mental status examination scale(MMSE)of the two groups were compared.Result:After intervention,the scores of the typeface transcription test,clock drawing test,line segmentation test,straight line bisecting test and plane graph copying test in the two groups were lower than those before intervention,and which in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).After intervention,FMA scores,MMSE scores and BI scores in both groups were higher than those before intervention,and which in the study group were higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion:On the basis of rehabilitation training combined with repeated transcranial magnetic stimulation to treat unilateral spatial neglect can effectively improve the clinical symptoms and cognitive function of patients,and enhance the independence and daily living ability of patients.